Latent TGF-beta bp1 Antibody (35409) [Alexa Fluor™ Plus 405]

• Reactivity: Hu
• Clone: 35409
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 405

Latent TGF-beta bp1 Antibody (35409) [Alexa Fluor™ Plus 405] Summary

• Specificity: Detects human LTBP-1 from the large latent TGF-beta 1 complex.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Latent TGF-beta bp1 Antibody (35409) [Alexa Fluor™ Plus 405]

• Latent TGFbeta bp1
• Latent TGF-beta bp1
• latent transforming growth factor beta binding protein 1
• latent-transforming growth factor beta-binding protein 1
• LTBP1
• LTBP-1
• MGC163161
• TGF-beta1-BP-1
• Transforming growth factor beta-1-binding protein 1

Background

TGF-beta  is synthesized as high molecular weight latent complexes. In platelets, the large latent TGF-beta 1 complex is composed of three components: mature TGF-beta 1 dimer; latency associated peptide; and a latent TGF-beta binding protein (LTBP) (1-3).The cDNAs for four binding proteins (LTBP-1, -2, -3 and -4) have now been cloned (4-5).

1. Miyazono, K. et al. (1991) EMBO J. 10:1091.
2. Moren, A. et al. (1994) J. Biol. Chem. 269:32469.
3. Yin, W. et al. (1995) J. Biol. Chem. 270:10147.
4. Kanzaki, T. et al. (1990) Cell 61:1051.
5. Saharinen, J. et al. (1998) J. Biol. Chem. 273:18459.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.