KMT3B/NSD1 Antibody (3E6) - Azide and BSA Free

Western Blot: KMT3B/NSD1 Antibody (3E6) [H00064324-M06] - Western Blot detection against Immunogen (37.62 KDa)

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 3E6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

KMT3B/NSD1 Antibody (3E6) - Azide and BSA Free Summary

• Immunogen: NSD1 (NP_071900, 2 a.a. ~ 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. DQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVSGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGSADGSESFQDPEKSDSRAQT
• Specificity: NSD1 - nuclear receptor binding SET domain protein 1 (3E6)
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: NSD1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for KMT3B/NSD1 Antibody (3E6) - Azide and BSA Free

• Androgen receptor coactivator 267 kDa protein
• Androgen receptor-associated protein of 267 kDa
• ARA267STO
• DKFZp666C163
• EC 2.1.1.43
• FLJ10684
• FLJ22263
• FLJ44628
• H3 lysine-36 and H4 lysine-20 specific
• KMT3BSotos syndrome
• Lysine N-methyltransferase 3B
• NR-binding SET domain-containing protein
• nuclear receptor binding SET domain protein 1

Background

This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NSD1
• Entrez:
  • 64324(Human)
• Uniprot:
  • NP_071900(Human)