KLHL12/C3IP1 Antibody

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Immunoprecipitation: KLHL12/C3IP1 Antibody [NBP1-49927] - Detection of Human KLHL12 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml
 

Independent Antibodies

       

Order Details

KLHL12/C3IP1 Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 150 and 200 of human Kelch-Like 12 using the numbering given in entry NP_067646.1 (GeneID 59349).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KLHL12
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoprecipitation 2-5 ug/mg lysate

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for KLHL12/C3IP1 Antibody

  • C3IP1kelch-like protein 12
  • CUL3-interacting protein 1
  • DKIR
  • FLJ27152
  • kelch-like 12 (Drosophila)
  • kelch-like protein C3IP1

Background

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. Component of an ubiquitin-protein E3 ligase complex which includes at least CUL3 and KLHL12. This complex interacts with DVL3 upon activation of the Wnt signaling pathway by WNT3A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional KLHL12/C3IP1 Products

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Diseases for KLHL12/C3IP1 Antibody (NBP1-49927)

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Bioinformatics

Gene Symbol KLHL12