Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. Component of an ubiquitin-protein E3 ligase complex which includes at least CUL3 and KLHL12. This complex interacts with DVL3 upon activation of the Wnt signaling pathway by WNT3A.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
59349 |
| Alternate Names |
- C3IP1kelch-like protein 12
- CUL3-interacting protein 1
- DKIR
- FLJ27152
- kelch-like 12 (Drosophila)
- kelch-like protein C3IP1
|
