Applications: WB, IHC
Host: Mouse monoclonal
Species: Hu, Mu, Rt
Host: Chicken Polyclonal
Applications: IP, WB (-)
Host: Rabbit Polyclonal
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. Component of an ubiquitin-protein E3 ligase complex which includes at least CUL3 and KLHL12. This complex interacts with DVL3 upon activation of the Wnt signaling pathway by WNT3A.
PTMs for KLHL12/C3IP1
Learn more about PTMs related to KLHL12/C3IP1.Ubiquitination
Bioinformatics Tool for KLHL12/C3IP1
Discover related pathways, diseases and genes to KLHL12/C3IP1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.