KIR2DL3/CD158b2 Antibody

Images

 
Western Blot: KIR2DL3/CD158b2 Antibody [H00003804-D01P] - Analysis of KIR2DL3 expression in transfected 293T cell line by KIR2DL3 polyclonal antibody.Lane 1: KIR2DL3 transfected lysate(37.90 KDa).Lane 2: Non-transfected ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

KIR2DL3/CD158b2 Antibody Summary

Immunogen
KIR2DL3 (NP_056952.2, 1 a.a. - 341 a.a.) full-length human protein. MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP
Specificity
Reacts with killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KIR2DL3
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for KIR2DL3/CD158b2 Antibody

  • CD158 antigen-like family member B2
  • CD158b2 antigen
  • CD158b2
  • CD158B2CD158b
  • cl-6
  • killer cell immunoglobulin-like receptor 2DL3
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
  • Killer inhibitory receptor cl 2-3
  • KIR-023GB
  • KIR2DL3
  • KIRCL23
  • KIR-K7b
  • KIR-K7c
  • MGC129943
  • MHC class I NK cell receptor
  • natural killer associated transcript 2
  • natural killer cell inhibitory receptor KIR2DL3
  • Natural killer-associated transcript 2
  • NKAT
  • NKAT2
  • NKAT-2
  • NKAT2A
  • nkat2b
  • NKAT2GL183
  • NK-receptor
  • p58 natural killer cell receptor clone CL-6
  • p58 NK receptor CL-6
  • p58
  • p58.2 MHC class-I specific NK receptor
  • p58.2 MHC class-I-specific NK receptor

Background

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol KIR2DL3
Entrez
Uniprot