KCNN1 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: KCNN1 Antibody [NBP2-57340] - Staining of human cell line U-2 OS shows localization to cytosol & actin filaments.

• Reactivity: Hu
• Applications: ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

KCNN1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit KCNN1 Antibody - BSA Free (NBP2-57340) is a polyclonal antibody validated for use in ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EDDEEDEAGRQRASGKPSNVGHR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KCNN1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
• Application Notes: Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  KCNN1 Recombinant Protein Antigen (NBP2-57340PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for KCNN1 Antibody - BSA Free

• hSK1
• KCa2.1
• KCNN1
• potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
• SK
• SK1
• SKCa 1
• SKCa1
• small conductance calcium-activated potassium channel protein 1

Background

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KCNN1