KCNN1 Products

Description

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. (provided by RefSeq)

Bioinformatics

Entrez	3780 Human 54261 Rat 84036 Mouse
Uniprot	NP_002239 Human Q92952 Human
Product By Gene ID	3780
Alternate Names	hSK1 KCa2.1 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 SK SK1 SKCa 1 SKCA1 small conductance calcium-activated potassium channel protein 1