KCC4/SLC12A7 Antibody (891526) [Alexa Fluor™ Plus 405]

• Reactivity: Hu
• Clone: 891526
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 405

KCC4/SLC12A7 Antibody (891526) [Alexa Fluor™ Plus 405] Summary

• Specificity: Detects human SLC12A7 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KCC4/SLC12A7 Antibody (891526) [Alexa Fluor™ Plus 405]

• DKFZp434F076
• KCC4
• KCC4Electroneutral potassium-chloride cotransporter 4
• K-Cl cotransporter 4
• potassium/chloride transporter KCC4
• SLC12A7
• solute carrier family 12 (potassium/chloride transporters), member 7
• solute carrier family 12 member 7

Background

Cation chloride cotransporters, including the potassium-chloride cotransporters (KCCs), are involved in the electroneutral movement of ions across the plasma membrane. SLC12A7 contains 12 membrane-spanning segments, 8 phosphorylation sites, 7 of which are in the C terminus, and 4 potential N-glycosylation sites. It is important for potassium recycling by siphoning potassium ions after their exit from outer hair cells into supporting Deiters cells, where potassium enters the gap junction pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.