Human reactivity reported in scientific literature (PMID: 25110711).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2) and 40% Glycerol
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for KCC3/SLC12A6 Antibody
agenesis of corpus callosum and peripheral neuropathy (Andermann syndrome)
Electroneutral potassium-chloride cotransporter 3
KCC3potassium chloride cotransporter 3
K-Cl cotransporter 3
potassium chloride cotransporter KCC3a-S3
solute carrier family 12 (potassium/chloride transporters), member 6
solute carrier family 12 member 6
SLC12A6 is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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