KCC3/SLC12A6 Antibody - BSA Free

Immunoprecipitation:KCC3/SLC12A6 AntibodyNBP3-29424] -Detection of human KCC3 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) prepared using RIPA buffer from Jurkat cells. Antibodies: Affinity purified rabbit anti-KCC3 antibody NBP3-29424 (lot NBP3-29424-1) used for IP at 6 µg per reaction. KCC3 was also immunoprecipitated by rabbit anti-KCC3 antibody for blotting immunoprecipitated KCC3, A304-409A-1 was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

• Reactivity: Hu
• Applications: IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

KCC3/SLC12A6 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit KCC3/SLC12A6 Antibody - BSA Free (NBP3-29424) is a polyclonal antibody validated for use in IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Between 75 and 125
• Assay Type: [Assay Type]
• Sample Volume: [Sample Volume]
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SLC12A6
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-citrate/phosphate buffer, pH 7 to 8
• Preservative: 0.09% Sodium Azide
• Purity: Affinity purified

Alternate Names for KCC3/SLC12A6 Antibody - BSA Free

• ACCPN
• agenesis of corpus callosum and peripheral neuropathy (Andermann syndrome)
• DKFZp434D2135
• EC 1.2.4.1
• EC 6.1.1.3
• Electroneutral potassium-chloride cotransporter 3
• KCC3
• KCC3A
• KCC3B
• KCC3potassium chloride cotransporter 3
• K-Cl cotransporter 3
• potassium chloride cotransporter KCC3a-S3
• potassium-chloride transporter-3a
• potassium-chloride transporter-3b
• SLC12A6
• solute carrier family 12 (potassium/chloride transporters), member 6
• solute carrier family 12 member 6

Background

SLC12A6 is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC12A6