KCC2/SLC12A5 Antibody (905705)

Images

 
Western blot shows lysates of human brain stem tissue. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human KCC2/SLC12A5 Monoclonal Antibody (Catalog # MAB8369) followed by HRP-conjugated Anti-Mouse IgG ...read more
HEK293 human embryonic kidney cell line transfected with human KCC2/SLC12A5 and eGFP was stained with either (A) Mouse Anti-Human KCC2/SLC12A5 Monoclonal Antibody (Catalog # MAB8369) or (B) Mouse IgG1 Isotype Control ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
905705
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

KCC2/SLC12A5 Antibody (905705) Summary

Immunogen
NS0 mouse myeloma cell line transfected with human SLC12A5
Accession # Q9H2X9
Specificity
Detects human SLC12A5 in ELISAs and Western blots.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SLC12A5
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5 ug/mL
  • Flow Cytometry 2.5 ug/10^6 cells
  • CyTOF-ready

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KCC2/SLC12A5 Antibody (905705)

  • Electroneutral potassium-chloride cotransporter 2
  • hKCC2
  • KCC2
  • KCC2K-Cl cotransporter 2
  • KIAA1176erythroid K-Cl cotransporter 2
  • Neuronal K-Cl cotransporter
  • SLC12A5
  • solute carrier family 12 (potassium/chloride transporter), member 5
  • solute carrier family 12 member 5

Background

Solute Carrier, family 12 (potassium/chloride transporter), member 5 (SLC12A5) encodes KCC2, a multi-pass co-transporter for K+ and Cl-.  KCC2/SLC12A5 is expressed on neurons, and is dysregulated in schizophrenia, spasticity, and affective disorders.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Diseases for KCC2/SLC12A5 Antibody (MAB8369)

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Bioinformatics

Gene Symbol SLC12A5
Entrez
Uniprot