KAL1 Antibody - BSA Free

Western Blot: KAL1 Antibody [NBP1-76580] - Western blot analysis of Anosmin in MCF7 cell lysate with Anosmin antibody at 1 ug/mL.

Immunocytochemistry/Immunofluorescence: KAL1 Antibody [NBP1-76580] - KAL1 in MCF7 cells with KAL1 antibody at 5 ug/mL.

Immunocytochemistry/ Immunofluorescence: KAL1 Antibody - BSA Free [NBP1-76580] - Immunofluorescence of KAL1 in MCF7 cells with KAL1 antibody at 20 ug/mL.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

KAL1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit KAL1 Antibody - BSA Free (NBP1-76580) is a polyclonal antibody validated for use in WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against an 18 amino acid synthetic peptide near the center of human Anosmin. The immunogen is located within amino acids 430 - 480 of Anosmin. Amino Acid Squence: KVYWKKTEDPTVNRYHVR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ANOS1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 5-20 ug/ml
  • Western Blot 1 ug/ml
• Control Peptide:

  KAL1 Peptide (NBP1-76580PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for KAL1 Antibody - BSA Free

• Adhesion molecule-like X-linked
• ADMLX
• ADMLXHHA
• ANOS1
• Anosmin 1
• anosmin-1
• HH1
• HHA
• KAL
• KAL1
• KALIG1
• KALIG-1
• Kallmann syndrome 1 sequence
• Kallmann syndrome interval gene 1
• Kallmann syndrome protein
• Kallmann syndrome-1 sequence (anosmin-1)
• KMS

Background

Mutations in Anosmin-1, an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ANOS1
• Uniprot:
  • NP_000207(Human)