IRF3 Antibody Pair

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Summary
Product Discontinued
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    • Catalog Number
      H00003661-AP11
    • Availability
      Product Discontinued

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IRF3 Antibody Pair Summary

Description
Quality control test: Standard curve using recombinant protein (H00003661-P02) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human IRF3.

  • Capture antibody: rabbit MaxPab affinity purified polyclonal anti-IRF3 (100 ug)
  • Detection antibody: mouse monoclonal anti-IRF3 IgG2a Kappa (20 ug)
  • Standard Curve Range
    3 ng/ml to 100 ng/ml
    Assay Type
    Sandwich ELISA
    Clonality
    Monoclonal
    Gene
    IRF3

    Applications/Dilutions

    Dilutions
    • Sandwich ELISA 3 ng/ml - 100 ng/ml

    Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    1x PBS, pH 7.4

    Notes

    This product is produced by and distributed for Abnova, a company based in Taiwan.

    Alternate Names for IRF3 Antibody Pair

    • interferon regulatory factor 3
    • IRF3
    • IRF-3

    Background

    IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. [provided by RefSeq]

    Limitations

    This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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    Blogs on IRF3.

    TRIF/TICAM1 and mitochondrial dynamics in the innate immune response
    TRIF, also known as toll like receptor adaptor molecule 1 or TICAM1, is known for its role in invading foreign pathogens as part of our innate immune response. TRIF/TICAM1 is a TIR-domain adaptor protein (toll/interleukin-1 receptor) that interacts...  Read full blog post.

    STING in Innate Immunity and Cancer: What’s the Buzz About?
    STING (STimulator of INterferon Genes protein) acts as a sensor of cytosolic DNA. Bacteria/Virus or self-derived DNA in the cytosol activates the STING pathway and promotes the production of type I interferons (IFN-alpha and IFN-beta). STING also ...  Read full blog post.

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    Bioinformatics

    Gene Symbol IRF3