Reactivity | HuSpecies Glossary |
Applications | Flow |
Clone | 482205 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Alexa Fluor 700 |
Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
Conjugate | Catalog # | Availability | Size | Price |
---|---|---|---|---|
Alexa Fluor 350 | FAB4019U-100UG | |||
Alexa Fluor 405 | FAB4019V-100UG | |||
Alexa Fluor 488 | IC4019G | |||
Alexa Fluor 594 | FAB4019T-100UG | |||
Alexa Fluor 647 | FAB4019R-100UG | |||
Alexa Fluor 750 | FAB4019S-100UG | |||
Allophycocyanin | IC4019A | |||
Unconjugated | MAB4019 | |||
Immunogen | E. coli-derived recombinant human IRF3 aa 206-427 Accession # Q14653 |
Specificity | Detects human IRF3 in Western blots. |
Source | N/A |
Isotype | IgG2b |
Clonality | Monoclonal |
Host | Mouse |
Gene | IRF3 |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells. |
Storage | Protect from light. Do not freeze.
|
Buffer | Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide. |
Preservative | 0.09% Sodium Azide |
Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
IRF3 (interferon response factor 3) is a 60 kDa member of the IRF family of proteins. Human IRF3 contains one DNA binding domain (aa 7‑107), a nuclear export signal (aa 139‑149) and multiple phosphorylation sites (aa 395‑407). Viral infection stimulates IRF3 phosphorylation, nuclear translocation and stimulation of IFN production. Alternate splice forms may exist. One will show a deletion of aa 201‑327, a second will show the same deletion plus an alternate start site at Met147, and a third will show a 125 aa substitution for the C-terminal 100 aa (aa 328‑427). Over aa 206‑427, human IRF3 is 76% and 83% aa identical to mouse and pig IRF3, respectively.
Secondary Antibodies |
Isotype Controls |
Alexa Fluor 350 | FAB4019U | |
Alexa Fluor 405 | FAB4019V | |
Alexa Fluor 488 | IC4019G | |
Alexa Fluor 594 | FAB4019T | |
Alexa Fluor 647 | FAB4019R | |
Alexa Fluor 700 | FAB4019N | |
Alexa Fluor 750 | FAB4019S | |
Allophycocyanin | IC4019A |
Diseases for IRF3 Antibody (FAB4019N)Discover more about diseases related to IRF3 Antibody (FAB4019N).
| Pathways for IRF3 Antibody (FAB4019N)View related products by pathway.
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PTMs for IRF3 Antibody (FAB4019N)Learn more about PTMs related to IRF3 Antibody (FAB4019N).
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TRIF/TICAM1 and mitochondrial dynamics in the innate immune response TRIF, also known as toll like receptor adaptor molecule 1 or TICAM1, is known for its role in invading foreign pathogens as part of our innate immune response. TRIF/TICAM1 is a TIR-domain adaptor protein (toll/interleukin-1 receptor) that interacts... Read full blog post. |
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