Integrin beta 7 Antibody

• Reactivity: Mu
• Applications: WB, Flow, CyTOF-ready
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

Integrin beta 7 Antibody Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin beta 7
  Glu20-His722
  Accession # P26011
• Specificity: Detects mouse Integrin beta 7 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse (rm) Integrin beta 1, rmIntegrin beta 2, recombinant human Integrin beta 3, and rmIntegrin beta 6 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ITGB7
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin beta 7 Antibody

• Gut homing receptor beta subunit
• integrin beta 7 subunit
• Integrin beta 7
• integrin beta-7
• integrin, beta 7
• ITGB7

Background

Integrin beta 7 is a 130 kDa type I transmembrane glycoprotein that belongs to the integrin beta chain family. It heterodimerizes with either Integrin alpha 4 or alpha E. Whereas, Integrin alpha E beta 7 is a receptor for E-Cadherin, Integrin alpha 4/ beta 7 is a receptor for fibronectin, MAdCAM 1 and VCAM1. The extracellular domain of mouse Integrin beta 7 shares 94% and 87% amino acid sequence identity with that of rat and human Integrin beta 7, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ITGB7
• Uniprot:
  • P26011()