Integrin beta 7 Products

Antibodies
Integrin beta 7 Antibody
Integrin beta 7 Antibody
AF4669
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Sheep Polyclonal
Conjugate Catalog # Availability Size Price
Integrin beta 7 Antibody (473 ...
Integrin beta 7 Antibody (473207) ...
MAB4669
Species: Hu
Applications: Flow, CyTOF-ready, ICC
Host: Mouse Monoclonal
Antibody Pairs
Integrin beta 7 Antibody Pair ...
Integrin beta 7 Antibody Pair
H00003695-PW1
Species: Hu
Applications: WB, IP
Lysates
Integrin beta 7 Overexpressio ...
Integrin beta 7 Overexpression Lys...
H00003695-T01
Species: Hu
Applications: WB
Integrin beta 7 Overexpressio ...
Integrin beta 7 Overexpression Lys...
NBL1-12076
Applications: WB
Proteins
Recombinant Human Integrin be ...
Recombinant Human Integrin beta 7 ...
H00003695-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human Integrin be ...
Recombinant Human Integrin beta 7 ...
H00003695-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Integrin beta 7 RNAi
Integrin beta 7 RNAi
H00003695-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Integrin beta7 is a 130 kD glycoprotein, also known as integin betap. It is a member of the Ig superfamily. In association with integrin alpha4 or alphaE chain, beta7 forms alpha4/ beta7 or alphaE/ beta7 heterodimer. alpha4/ beta7 (CD49d/ beta7, LPAM-1) is expressed on majority of peripheral lymphocytes, small subsets of thymocytes and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion, some hematopoietic progenitor cells migration. alphaE/ beta7 (CD103/ beta7, alphaIEL/ beta7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/ beta7 complex is thought to play a role in lymphocyte retention via interaction with its lignd E-Cadherin. The Fib504 antibody has been reported to react with mouse and human beta7 integrin and to block beta7 integrin-mediated cell adhesion in in vitro and in vivo studies.

Bioinformatics

Entrez Human
Mouse
Mouse
Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 3695
Alternate Names
  • integrin beta-7
  • integrin beta 7 subunit
  • Gut homing receptor beta subunit
  • integrin, beta 7

Pathways for Integrin beta 7

View related products by pathway and learn more about each of the pathways below.

Cell Adhesion
Pathogenesis
Drug Resistance
Menstruation
Flight
Cell Cycle
Fertilization

Research Areas for Integrin beta 7

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

PTMs for Integrin beta 7

Learn more about PTMs related to Integrin beta 7.

Sumoylation
Phosphorylation

Bioinformatics Tool for Integrin beta 7

Discover related pathways, diseases and genes to Integrin beta 7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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