Integrin alpha V beta 5 Antibody (P5H9) [Allophycocyanin]

MCF-7 human breast cancer cell line was stained with Mouse Anti-Human Integrin aV beta 5 APC-conjugated Monoclonal Antibody (Catalog # FAB2528A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Hu
• Applications: Flow
• Clone: P5H9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

Integrin alpha V beta 5 Antibody (P5H9) [Allophycocyanin] Summary

• Immunogen: HT1080 human fibrosarcoma cell line
• Specificity: Detects human Integrin alpha V beta 5. Recognizes the human Integrin alpha V beta 5 heterodimer and does not recognize the alpha V subunit in association with any other beta subunits.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ITGAV
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin alpha V beta 5 Antibody (P5H9) [Allophycocyanin]

• CD51
• Integrin alpha V beta 5
• integrin subunit alpha V
• ITGAV
• MSK8
• VNRA
• VTNR

Background

Integrins are heterodimeric receptors comprised of an alpha and a beta subunit. Integrin alpha V (CD51) associates with several different beta subunits, but Integrin beta 5 associates exclusively with the alpha V subunit. Integrin alpha V beta 5, also known as Integrin alpha V beta S and Integrin alpha V beta 3B, is a transmembrane heterodimeric protein that functions as a receptor for Vitronectin. It is expressed on hepatoma cells, fibroblasts and carcinoma cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Integrin alpha V beta 5 Antibody (FAB2528A)(1)

Publication using FAB2528A

• Davies, DM;Pugliese, G;Parente Pereira, AC;Whilding, LM;Larcombe-Young, D;Maher, J; Engineering a Dual Specificity ?? T-Cell Receptor for Cancer Immunotherapy Biology 2024-03-20 [PMID: 38534465] (Flow Cytometry, Human)

Bioinformatics

• Gene Symbol: ITGAV