Integrin alpha D/CD11d Antibody

Immunohistochemistry-Paraffin: Integrin alpha D/CD11d Antibody [NBP1-90237] - Staining of human spleen shows moderate membranous positivity in endothelial cells and a subset of cells in white pulp.

Immunohistochemistry-Paraffin: Integrin alpha D/CD11d Antibody [NBP1-90237] - Staining of human pancreas shows no membranous positivity in exocrine glandular cells as expected.

Immunohistochemistry-Paraffin: Integrin alpha D/CD11d Antibody [NBP1-90237] - Staining of human prostate shows no membranous positivity in glandular cells as expected.

Immunohistochemistry-Paraffin: Integrin alpha D/CD11d Antibody [NBP1-90237] - Staining of human tonsil shows moderate membranous positivity in endothelial cells.

Product Discontinued

Integrin alpha D/CD11d Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: RCWEEKPSALEAGDATVCLTIQKSSLDQLGDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCVEDVVSPIILHLNFSLV
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ITGAD
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH6 retrieval is recommended. Use in WB reported in scientific literature (PMID: 30650373).

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 30650373).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Integrin alpha D/CD11d Antibody

• ADB2
• CD11 antigen-like family member D
• CD11d
• FLJ39841
• Integrin alpha D
• integrin alpha-D
• integrin, alpha D
• Leukointegrin Alpha D

Background

Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Integrin alpha D/CD11d Antibody (NBP1-90237)(1)

Publication using NBP1-90237

• Lin C, Zhang Y, Zhang K et al. Fever Promotes T Lymphocyte Trafficking via a Thermal Sensory Pathway Involving Heat Shock Protein 90 and a4 Integrins Immunity 2019-01-15 [PMID: 30650373] (WB, Mouse)

Bioinformatics

• Gene Symbol: ITGAD
• Entrez:
  • 3681(Human)
• Uniprot:
  • Q13349(Human)