IMP5 Antibody [HRP]

Product Discontinued

IMP5 Antibody [HRP] Summary

• Immunogen: intramembrane protease 5. (Uniprot# Q8IUH8)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SPPL2C
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for IMP5 Antibody [HRP]

• EC 3.4.23
• EC 3.4.23.-
• IMP-5
• intramembrane protease 5
• signal peptide peptidase-like 2C
• SPPL2c
• SPP-like 2C

Background

IMP5 is a protein that functions as an intramembrane-cleaving aspartic protease, and may have the ability to cleave type II membrance signal peptides in the membrane's hydrophobic plane, and is encoded by a gene made up of 684 amino acids and a mass of approximately 74.5 kDa. Current studies are being done on several diseases and disorders relating to this protein, including suprenuclear palsy, Parkinson's disease, and malaria. IMP5 has also been shown to have interactions with BAP1, TAF1D, and DTNBP1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SPPL2C