IMP5 Antibody [Alexa Fluor® 750]

Product Discontinued

IMP5 Antibody [Alexa Fluor® 750] Summary

• Immunogen: intramembrane protease 5. (Uniprot# Q8IUH8)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SPPL2C
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IMP5 Antibody [Alexa Fluor® 750]

• EC 3.4.23
• EC 3.4.23.-
• IMP-5
• intramembrane protease 5
• signal peptide peptidase-like 2C
• SPPL2c
• SPP-like 2C

Background

IMP5 is a protein that functions as an intramembrane-cleaving aspartic protease, and may have the ability to cleave type II membrance signal peptides in the membrane's hydrophobic plane, and is encoded by a gene made up of 684 amino acids and a mass of approximately 74.5 kDa. Current studies are being done on several diseases and disorders relating to this protein, including suprenuclear palsy, Parkinson's disease, and malaria. IMP5 has also been shown to have interactions with BAP1, TAF1D, and DTNBP1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SPPL2C