Recombinant Human IMMP2L His Protein

SDS-Page: IMMP2L Recombinant Protein [NBP2-51812] - 15% SDS Page (3 ug)

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Human IMMP2L His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 38-175 of Human IMMP2L
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSRVEGASM QPSLNPGGSQ SSDVVLLNHW KVRNFEVHRG DIVSLVSPKN PEQKIIKRVI ALEGDIVRTI GHKNRYVKVP RGHIWVEGDH HGHSFDSNSF GPVSLGLLHA HATHILWPPE RWQKLESVLP PERLPVQREE E

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: IMMP2L
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 18 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 50% glycerol, 1 mM DTT
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >95%, by SDS-PAGE

Alternate Names for Recombinant Human IMMP2L His Protein

• EC 3.4.21
• EC 3.4.21.-
• IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
• IMP2 inner mitochondrial membrane protease-like (S. cerevisiae)
• IMP2inner mitochondrial membrane peptidase 2 like
• IMP2-like protein
• IMP2-LIKE
• mitochondrial inner membrane protease subunit 2

Background

IMMP2L is a gene that codes for a protein whose function is to catalyze the removal of transit peptides that are required in order to target protein from the mitochondrial matrix into the inter-membrane space in all tissues except the liver and lung. IMMP2L has a length of 175 amino acids and a weight of approximately 20 kDa, and it has a shorter isoform comprised of 110 amino acids with a weight of approximately 12 kDa. Current studies are being done on diseases and disorders related to this gene including Tourette syndrome and malaria. IMMP2L has also been shown to have interactions with ALDH1B1, GPX4, GUF1, HACL1, and IDO2 in pathways such as the protein export pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: IMMP2L