IL18R1 Antibody (11) [Allophycocyanin]

• Reactivity: Hu
• Applications: ELISA, ELISA
• Clone: 11
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Allophycocyanin

IL18R1 Antibody (11) [Allophycocyanin] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human IL18R1 (Accession#: NP_003846.1; Met 1-Arg 329).
• Specificity: No cross-reactivity in ELISA with:
  
  Mouse IL18R1 / IL1RRP / CD218a
  Mouse SIGIRR
  Human IL1R1 / CD121a
  Human IL1R2 / IL1RB / CD121b
  Human IL1R3 / IL1RAP
  Human IL1R8 / IL1RAPL1
  Human IL1RL1 / IL1R4 / ST2
  Human IL18RAP / IL1R7
  Human IL1R9 / IL1RAPL2
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: IL18R1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA Capture
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Alternate Names for IL18R1 Antibody (11) [Allophycocyanin]

• CD218 antigen-like family member A
• CD218a antigen
• CD218a
• CDw218a
• cytokine receptor
• IL-18R1
• IL-18R-1
• IL1R-rp
• IL1RRPIL1 receptor-related protein
• IL-1RrpIL18RA
• interleukin 18 receptor 1
• interleukin-18 receptor 1

Background

IL-18 receptor is composed of an alpha and a beta subunit that combine to form a high affinity receptor for IL-18. IL-18 receptor alpha chain, also known as CDw218a, is a 75-80 kD type I transmembrane protein. It is expressed on NK cells, neutrophils, endothelial cells, and subsets of T and B cells. The expression of CDw218a on lymphocytes is upregulated after activation. The interaction of IL-18 and IL-18 receptor has been reported to be implicated in promotion of Th1 cytokine production and atherogenesis. The H44 antibody is specific for IL-18 receptor alpha chain and has been reported to block IL-18 binding to the receptor and to be useful for the identification of IL-18 receptor by flow cytometry and IHC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL18R1