IL-2 R beta Antibody (TM-b1) - Azide and BSA Free

Flow Cytometry: IL-2 R beta Antibody (TM-b1) - Azide Free [NBP2-53132] - Staining of C57Bl/6 splenocytes with Anti-Mouse NK1.1 APC and 0.25 ug of Rat IgG2b K Isotype Control Purified (left) or 0.5 ug of Anti-Mouse CD122 Purified (right) followed by Anti-Rat IgG Biotin and Streptavidin PE . Cells in the lymphocyte gate were use

• Reactivity: Mu
• Applications: Flow, IP, B/N, CyTOF-ready
• Clone: TM-b1
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1 mg/ml

IL-2 R beta Antibody (TM-b1) - Azide and BSA Free Summary

• Immunogen: The immunogen for this antibody was Purified CD122.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat
• Gene: IL2RB
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • CyTOF-ready
  • Flow Cytometry 1:10 - 1:1000
  • Immunoprecipitation 1:10 - 1:500

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.2)
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for IL-2 R beta Antibody (TM-b1) - Azide and BSA Free

• CD122 antigen
• CD122
• high affinity IL-2 receptor beta subunit
• High affinity IL-2 receptor subunit beta
• IL-15 R beta
• IL-2 R beta
• IL-2 receptor subunit beta
• IL2R beta
• IL-2R subunit beta
• IL2RB
• IL-2Rb
• interleukin 15 receptor, beta
• interleukin 2 receptor, beta
• interleukin-2 receptor subunit beta
• P70-75
• p75

Background

The TM-beta1 monoclonal antibody reacts with mouse CD122, the 90-110 kDa interleukin-2 receptor beta chain (IL-2Rbeta). CD122 is expressed by NK cells and some T cells in the periphery, and is upregulated by activation. CD122 associates with CD25 and CD132 (common gamma chain) to form the high affinity IL-2 receptor. High affinity binding of IL-2 to the IL-2 receptor is inhibited by the TM-beta1 antibody.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL2RB