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202-IL) stimulates proliferation in the MO7e human megakaryocytic leukemic cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human IL-2 (30 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human IL-2 R beta Monoclonal Antibody (Catalog # MAB224). The ND50 is typically 0.05-0.15 µg/mL." class="big_lightbox" target="_blank">
202-IL) stimulates proliferation in the MO7e human megakaryocytic leukemic cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human IL-2 (20 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human IL-2 R beta Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-224-NA). The ND50 is typically 10‑30 µg/mL." class="big_lightbox" target="_blank">
AVI10459) is immobilized at 0.25 µg/mL (100 µL/well), Recombinant Human IL-15 (247-ILB) binds with an ED50 of 1-6 ng/mL." class="big_lightbox" target="_blank">
AVI10459) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 36-45 kDa." class="big_lightbox" target="_blank">
247-ILB) dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 1.75-14.0 μg/mL." class="big_lightbox" target="_blank">
The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolysis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown.
![Neutralization IL-2 R beta Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/IL-2_R_beta_AF-224-NA_Block_Neutralize_541.jpg)
![Simple Western IL-2 R beta Antibody (27311) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab2241_human-il-2-r-beta-mab-clone-27311-simple-western-305202315358.jpg)
![Binding Activity IL-2 R beta [Biotin]](http://images.novusbio.com/images/protein/avi10459_recombinant-human-il-2-r-beta-his-tag-avi-tag-protein-cf-binding-activity-1452020155816.jpg)
![Bioactivity IL-2 R beta [Unconjugated]](http://images.novusbio.com/images/10919-2b_recombinant-human-il-2-r-beta-fc-chimera-protein-cf-bioactivity-1052022112624.jpg)
![Simple Western IL-2 R beta Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/af-224-na_human-il-2-r-beta-affinity-purified-polyclonal-ab-simple-western-3052023154030..jpg)
![SDS-Page IL-2 R beta [Biotin]](http://images.novusbio.com/images/protein/IL2_R_beta_AVI10459_3172.jpg)
![Binding Activity IL-2 R beta [Biotin]](http://images.novusbio.com/images/avi10919_recombinant-human-il-2-r-beta-fc-chimera-avi-tag-protein-cf-binding-activity-16122021133022.jpg)
![SDS-Page IL-2 R beta [Biotin]](http://images.novusbio.com/fullsize/avi10919_recombinant-human-il-2-r-beta-fc-chimera-avi-tag-protein-cf-sds-page-9112021141849.jpg)
![SDS-Page IL-2 R beta [Unconjugated]](http://images.novusbio.com/fullsize/10919-2b_recombinant-human-il-2-r-beta-fc-chimera-protein-cf-sds-page-105202211282.jpg)
