IL-1ra/IL-1F3/IL1RN Antibody Summary
Recombinant fragment corresponding to a region within amino acids 1 and 177 of IL1ra antagonist (Uniprot ID#P18510)
Isoform 1: Secreted, Isoform 2: Cytoplasm, Isoform 3: Cytoplasm, Isoform 4: Cytoplasm
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0).
Immunogen affinity purified
- Western Blot 1:500-1:3000
- Immunocytochemistry/Immunofluorescence 1:100-1:1000
Dog (83%), Pig (82%), Bovine (81%)
Alternate Names for IL-1ra/IL-1F3/IL1RN Antibody
- interleukin 1 receptor antagonist
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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