IKK gamma Antibody (72C627) [HRP]

• Reactivity: Hu, Mu
• Applications: WB
• Clone: 72C627
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: HRP

IKK gamma Antibody (72C627) [HRP] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: This antibody was raised against a His-tagged full-length human IKK3/IKKg protein.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: IKBKG
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB100-56542. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.
• Antagonist:
  • IKK gamma Inhibitor Peptide Set NBP2-26504
• Readout System:
  • NovaLume Plus Chemiluminescent Reagent LUM-555

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IKK gamma Antibody (72C627) [HRP]

• FIP-3IP2
• FIP3NF-kappa-B essential modifier
• FIP3P
• I-kappa-B kinase subunit gamma
• IkB kinase gamma subunit
• IkB kinase subunit gamma
• IkB kinase-associated protein 1
• IKBKG
• IKK gamma
• IKKAP1
• IKKG
• IKK-gammaIPD2
• incontinentia pigmenti
• inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
• Inhibitor of nuclear factor kappa-B kinase subunit gamma
• IP
• IP1
• NEMO
• NEMOAMCBX1
• NFkappaB essential modulator
• NF-kappa-B essential modulator

Background

Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males (The International Incontinentia Pigmenti Consortium, 2000 [PubMed 10839543]). In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation. Familial incontinentia pigmenti is caused by mutations in the NEMO gene and is here referred to as IP2, or 'classical' incontinentia pigmenti. Sporadic incontinentia pigmenti, the so-called IP1, which maps to Xp11, is categorized as hypomelanosis of Ito (MIM 300337).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IKBKG