IKK gamma Products

Antibodies
IKK gamma Antibody [Unconjuga ...
IKK gamma Antibody [Unconjugated]
AF2684
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC
Host: Goat Polyclonal
Inhibitors
IKK gamma Inhibitor Peptide S ...
IKK gamma Inhibitor Peptide Set
NBP2-26504
Species: Hu, Mu, Rt
Applications: Func-Inh, In vitro, In vivo
Lysates
IKK gamma Overexpression Lysa ...
IKK gamma Overexpression Lysate (N...
NBP2-10944
Applications: WB
IKK gamma Overexpression Lysa ...
IKK gamma Overexpression Lysate (N...
NBP2-04192
Applications: WB
IKK gamma Overexpression Lysa ...
IKK gamma Overexpression Lysate (N...
NBP2-04253
Applications: WB
Proteins
Recombinant Human IKK gamma P ...
Recombinant Human IKK gamma Protein
H00008517-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human IKK gamma P ...
Recombinant Human IKK gamma Protein
H00008517-Q01
Species: Hu
Applications: WB, ELISA, PA
IKK gamma Recombinant Protein ...
IKK gamma Recombinant Protein Antigen
NBP1-84681PEP
Species: Hu
Applications: AC
RNAi
IKK gamma RNAi
IKK gamma RNAi
H00008517-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males (The International Incontinentia Pigmenti Consortium, 2000 [PubMed 10839543]). In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation. Familial incontinentia pigmenti is caused by mutations in the NEMO gene and is here referred to as IP2, or 'classical' incontinentia pigmenti. Sporadic incontinentia pigmenti, the so-called IP1, which maps to Xp11, is categorized as hypomelanosis of Ito (MIM 300337).[supplied by OMIM]

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 8517
Alternate Names
  • NFkappaB essential modulator
  • IKKG
  • NF-kappa-B essential modulator
  • IKKAP1
  • IkB kinase gamma subunit
  • Inhibitor of nuclear factor kappa-B kinase subunit gamma
  • IkB kinase-associated protein 1
  • IkB kinase subunit gamma
  • IP1
  • incontinentia pigmenti
  • IP
  • Fip3p
  • IKK-gammaIPD2
  • FIP-3IP2
  • NEMOAMCBX1
  • FIP3NF-kappa-B essential modifier
  • I-kappa-B kinase subunit gamma
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

Research Areas for IKK gamma

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Immunology
Innate Immunity
Phospho-Specific

PTMs for IKK gamma

Learn more about PTMs related to IKK gamma.

Phosphorylation
Ubiquitination
Sumoylation
Cleavage
Ribosylation
Methylation

Bioinformatics Tool for IKK gamma

Discover related pathways, diseases and genes to IKK gamma. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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Related IKK gamma Blog Posts

Check out the latest blog posts on IKK gamma.
Regulating Immune Response Pathways with IKK beta
IKK beta, also known as IKK2, activates the NFkB complex by phosphorylating the NFkB inhibitor, IkBa. Several transcript variants, some protein-coding and some not, have been found for IKKB. The Nuclear Factor-kappa B (NF-kB) family of transcription f...    Read more.
Read more IKK gamma related blogs.