IGSF2/CD101 Antibody (307707) [Biotin]

• Reactivity: Mu
• Applications: Flow, ICC/IF
• Clone: 307707
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Biotin
• Concentration: LYOPH

IGSF2/CD101 Antibody (307707) [Biotin] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant mouse IGSF2/CD101
  Arg21-Leu1033
  Accession # NP_997088
• Specificity: Detects mouse IGSF2/CD101.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: CD101
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 2.5 ug/10^6 cells
  • Immunocytochemistry 8-25 ug/mL
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IGSF2/CD101 Antibody (307707) [Biotin]

• CD101 antigen
• CD101 molecule
• CD101
• Cell surface glycoprotein V7
• EWI101
• EWI-101
• Glu-Trp-Ile EWI motif-containing protein 101
• IGSF2
• Leukocyte Surface Protein
• member 2
• V7

Background

IGSF2, also known as CD101, is an Ig-superfamily transmembrane protein. It is expressed on dendritic cells, Langerhans cells, granulocytes, and activated T cells. IGSF2 ligation is involved in T cell activation. Polymorphisms in IGSF2 are associated with susceptibility to type I diabetes. The extracellular domains of mouse and human IGSF2 share 70% amino acid sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for IGSF2/CD101 Antibody (BAM3368)(1)

Publication using BAM3368

• Calderon B, Suri A, Miller MJ Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules. Proc. Natl. Acad. Sci. U.S.A., 2008-04-21;105(16):6121-6. 2008-04-21 [PMID: 18427107] (Flow Cytometry, Mouse)

Bioinformatics

• Gene Symbol: CD101
• Uniprot:
  • NP_997088()