Applications: Flow, CyTOF-ready
Host: Rat Monoclonal
Applications: Flow, IHC, IHC-Fr, IP
Host: Mouse Monoclonal
Applications: WB, ELISA, PA, AP
CD101 is a disulfide-linked homodimeric type 1 glycoprotein. The peptide is comprised of 7 extracellular V-type IgSF domains. CD101 is highly expressed on monocytes, granulocytes, mucosal T cells, and on activated peripheral blood T cells. Expression is weak on resting T and B and NK cells, absent from platelets and weak or absent from most hematopoietic cell lines. CD101 is thought to play a co-stimulatory role in TCR/CD3-mediated T cell activation. Monoclonal antibodies against CD101 inhibit allogeneic T cell responses. Studies suggest that CD101 plays a major role in the activation of T cells by skin dendritic cells.
|Product By Gene ID
- CD101 antigen
- Glu-Trp-Ile EWI motif-containing protein 101
- Cell surface glycoprotein V7
- leukocyte surface protein
- member 2
- CD101 molecule
Bioinformatics Tool for IGSF2/CD101
Discover related pathways, diseases and genes to IGSF2/CD101. Need help? Read the Bioinformatics Tool Guide
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