IGFBP-3 Recombinant Protein


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Product Details

Reactivity HuSpecies Glossary

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IGFBP-3 Recombinant Protein Summary

A recombinant protein corresponding to 264 amino acids of Human IGFBP-3

Source: E. coli

Amino Acid Sequence: The amino acid sequence of this product is not available.
E. coli
Details of Functionality
The EDSO as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is <0.2, in the presence of 15 ng/ml of human IGF-II.
Endotoxin Note
<0.1 ng/ug

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
Sterile filtered and20 mM HCl.
Reconstitution Instructions
Reconstitute with water to a final concentration of 0.1 - 1.0 mg/ml.


After reconstituted, dilute further with other aqueous solutions.

Alternate Names for IGFBP-3 Recombinant Protein

  • acid stable subunit of the 140 K IGF complex
  • binding protein 29
  • binding protein 53
  • growth hormone-dependent binding protein
  • IBP-3
  • IBP3BP-53
  • IGF-binding protein 3
  • IGFBP3
  • IGFBP-3
  • insulin-like growth factor binding protein 3
  • insulin-like growth factor-binding protein 3


Human IGF-BP3, also known as growth-hormone-dependant binding protein, is a 28.9 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals. In addition to its ability to modulate the activity of IGF-I and IGF-2, IGF-BP3 also exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors such as Bombesin, Vasopressin, PDGF, and EGF. Recombinant human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Contact Information

Product PDFs


Gene Symbol IGFBP3

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