Human IGFBP-3 ELISA Kit (Colorimetric)

Product Discontinued

Human IGFBP-3 ELISA Kit (Colorimetric) Summary

• Description: IGFBP3 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human IGFBP3.
• Standard Curve Range: 156 to 10000 pg/mL
• Sensitivity: 10 pg/mL
• Assay Type: Sandwich ELISA
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: IGFBP3

Applications/Dilutions

• Dilutions:
  • ELISA
  • Quantification
• Application Notes: Useful for quantification.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Human IGFBP-3 ELISA Kit (Colorimetric)

• acid stable subunit of the 140 K IGF complex
• binding protein 29
• binding protein 53
• growth hormone-dependent binding protein
• IBP-3
• IBP3BP-53
• IGF-binding protein 3
• IGFBP3
• IGFBP-3
• insulin-like growth factor binding protein 3
• insulin-like growth factor-binding protein 3

Background

IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for IGFBP-3 ELISA Kit (KA0353)(4)

Publications using KA0353

• Suzuki S, Morimoto S, Fujishiro M et al. Inhibition of the insulin-like growth factor system is a potential therapy for rheumatoid arthritis. Autoimmunity. 2014-10-29 [PMID: 25352179]
• Spagnoli A, Torello M, Nagalla SR et al. Identification of STAT-1 as a molecular target of IGFBP-3 in the process of chondrogenesis. J Biol Chem. 2002-05-24 [PMID: 11886859]
• Weinzimer SA, Gibson TB, Collett-Solberg PF et al. Transferrin is an insulin-like growth factor-binding protein-3 binding protein. J Clin Endocrinol Metab. 2001-04-01 [PMID: 11297622]
• Deal C, Ma J, Wilkin F et al. Novel promoter polymorphism in insulin-like growth factor-binding protein-3: correlation with serum levels and interaction with known regulators. J Clin Endocrinol Metab. 2001-03-01 [PMID: 11238520]

FAQs for IGFBP-3 ELISA Kit (KA0353). (Showing 1 - 2 of 2 FAQs).

1. I am interested in your IGFBP-3 ELISA kits. Do you have any information as to whether it have ever been used in dogs?
   • The immunogen used for this antibody to IGFBP-3 is not homologous enough for me to recommend its use in dogs.
2. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: IGFBP3