IgE Antibody

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated

Order Details

IgE Antibody Summary

Immunogen
BALB/c mouse IgE paraproteins
Specificity
This product recognizes the heavy chains of BALB/c mouse IgE. It has been cross adsorbed against mouse IgG1, IgG2a, IgG2b, IgG3, IgM and IgA.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
IGHE
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
BBS (pH 8.2)
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for IgE Antibody

  • IgE
  • immunoglobulin heavy constant epsilon

Background

IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are ~150 ng/ml, compared to 10 mg/ml for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity.

There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans.

IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional IgE Products

Bioinformatics Tool for IgE Antibody (NBP1-45157)

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Diseases for IgE Antibody (NBP1-45157)

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Pathways for IgE Antibody (NBP1-45157)

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Research Areas for IgE Antibody (NBP1-45157)

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Blogs on IgE.

Understanding the Importance of Human IgG
Human IgG is a component of the immune system that protects the body from infection. It is the most abundantly found antibody isotype within the circulatory system of the human body. All antibody isotypes contain two heavy chains and two light chains...  Read full blog post.

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Bioinformatics

Gene Symbol IGHE