IgE Antibody - BSA Free

• Reactivity: Mu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Format: BSA Free

IgE Antibody - BSA Free Summary

• Description: Novus Biologicals Goat IgE Antibody - BSA Free (NBP1-45157) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: BALB/c mouse IgE paraproteins
• Specificity: This product recognizes the heavy chains of BALB/c mouse IgE. It has been cross adsorbed against mouse IgG1, IgG2a, IgG2b, IgG3, IgM and IgA.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: IGHE
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Borate buffered saline (pH 8.2)
• Preservative: <0.1% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for IgE Antibody - BSA Free

• IgE
• immunoglobulin heavy constant epsilon

Background

IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are ~150 ng/ml, compared to 10 mg/ml for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity.

There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans.

IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IGHE