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IgE Antibody (5D4cc)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clone
5D4cc
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-8331AF350
Alexa Fluor 405
NB110-8331AF405
Alexa Fluor 488
NB110-8331AF488
Alexa Fluor 532
NB110-8331AF532
Alexa Fluor 594
NB110-8331AF594
Alexa Fluor 647
NB110-8331AF647
Alexa Fluor 700
NB110-8331AF700
Alexa Fluor 750
NB110-8331AF750
Biotin
NB110-8331B
DyLight 350
NB110-8331UV
DyLight 405
NB110-8331V
DyLight 488
NB110-8331G
DyLight 550
NB110-8331R
DyLight 594
NB110-8331DL594
DyLight 650
NB110-8331C
DyLight 680
NB110-8331FR
DyLight 755
NB110-8331IR
FITC
NB110-8331F
HRP
NB110-8331H
Janelia Fluor 549
NB110-8331JF549
Janelia Fluor 646
NB110-8331JF646
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IgE Antibody (5D4cc) Summary

Immunogen
Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with IgE from myelomatous human serum.
Specificity
Specific for IgE C epsilon 2-domain specific
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
IGHE
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Sandwich ELISA 1:1000000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for IgE Antibody (5D4cc)

  • IgE
  • immunoglobulin heavy constant epsilon

Background

IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are approx. 150 ng/ml, compared to 10 mg/ml for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity. There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans. IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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IgE Antibody
(5D4cc)
NB110-8331
IgE Antibody (5D4cc)
Species: Hu
Applications: ELISA

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Bioinformatics

Gene Symbol IGHE
Entrez