IgE Antibody (5D4cc)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, S-ELISA
Clone
5D4cc
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

IgE Antibody (5D4cc) Summary

Immunogen
Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with IgE from myelomatous human serum
Specificity
Specific for IgE C epsilon 2-domain specific
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
IGHE
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Sandwich ELISA 1:1000000
Application Notes
Recommended pairs (capture-detection): NB110-8331 - NB110-8330

Reactivity Notes

Cross-reacts with Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for IgE Antibody (5D4cc)

  • IgE
  • immunoglobulin heavy constant epsilon

Background

IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are approx. 150 ng/ml, compared to 10 mg/ml for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity. There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans. IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for IgE Antibody (NB110-8331)

Discover related pathways, diseases and genes to IgE Antibody (NB110-8331). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for IgE Antibody (NB110-8331)

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Pathways for IgE Antibody (NB110-8331)

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Research Areas for IgE Antibody (NB110-8331)

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Blogs on IgE.

Understanding the Importance of Human IgG
Human IgG is a component of the immune system that protects the body from infection. It is the most abundantly found antibody isotype within the circulatory system of the human body. All antibody isotypes contain two heavy chains and two light chains ...  Read full blog post.

Omicron Variant Antibodies

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Calculators

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Bioinformatics

Gene Symbol IGHE
Entrez