ID1 Antibody [Alexa Fluor® 350]

• Reactivity: Hu, Mu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 350

ID1 Antibody [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant mouse ID1
  Met1-Glu135
  Accession # P20067
• Specificity: Detects human and mouse ID1 in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ID1 Antibody [Alexa Fluor® 350]

• BHLHB24
• bHLHb24DNA-binding protein inhibitor ID-1
• Class B basic helix-loop-helix protein 24
• dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helixprotein)
• dJ857M17.1.2
• ID
• ID1
• inhibitor of differentiation 1
• Inhibitor of DNA binding 1
• inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

Background

ID-1a is a negative regulator of helix-loop-helix (HLH) DNA binding proteins. ID-1a contains a HLH motif but no DNA binding motif, therefore, upon binding other HLH proteins, ID-1a acts a dominant negative regulator. ID-1a can be found in both cytoplasmic and nuclear cell fractions. Increased ID-1a expression is associated with cellular proliferation and cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.