Recombinant Human ICAT/CTNNBIP1 Protein

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SDS-Page: ICAT/CTNNBIP1 Protein [NBP1-45266] - 15% SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human ICAT/CTNNBIP1 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-81 of Human ICAT/CTNNBIP1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MNREGAPGKS PEEMYIQQKV RVLLMLRKMG SNLTASEEEF LRTYAGVVNS QLSQLPPHSI DQGAEDVVMA FSRSETEDRR Q

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
CTNNBIP1
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
11.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human ICAT/CTNNBIP1 Protein

  • beta-catenin-interacting protein ICAT
  • catenin, beta interacting protein 1
  • CTNNBIP1
  • ICAT
  • ICATbeta-interacting protein 1
  • Inhibitor of beta-catenin and Tcf-4

Background

CTNNBIP1 binds CTNNB1 and prevents interaction between CTNNB1 and TCF (T-cell transcription factor) family members. This protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. Recombinant human CTNNBIP1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol CTNNBIP1
Entrez