ICA1 Antibody [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB, IHC, CyTOF-ready, Flow
• Clonality: Polyclonal
• Host: Goat
• Conjugate: mFluor Violet 450 SE

ICA1 Antibody [mFluor Violet 450 SE] Summary

• Immunogen: E. coli-derived recombinant human ICA1
  Ser2-Ala482
  Accession # ABW03414
• Specificity: Detects human ICA1 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ICA1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Immunohistochemistry
  • Intracellular Staining by Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ICA1 Antibody [mFluor Violet 450 SE]

• diabetes mellitus type I autoantigen
• ICA1
• ICA69
• ICAp69
• ICAp69Islet cell autoantigen p69,69 kDa islet cell autoantigen
• islet cell autoantigen 1 (69kD)
• islet cell autoantigen 1 isoform
• islet cell autoantigen 1
• islet cell autoantigen 1, 69kDa
• p69

Background

ICA1 is a gene that codes for a protein that is an autoantigen and may play a role in neurotransmitter secretion and is expressed abundantly in the pancreas, heart and brain, with a length of 483 amino acids and a weight of approximately 55 kDa. Current studies are being done on several diseases and disorders related to this gene including diabetes mellitus, Sjogren's syndrome, rehumatiod arthritis, insulinoma, vitiligo, and thyroiditis. ICA1 has also been shown to have interactions with KRT33B, STK16, CNTF, MKKS, and MYC in pathways such as the type 1 diabetes mellitus pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ICA1