Hyaluronidase 1/HYAL1 Antibody - BSA Free

Western Blot: Hyaluronidase 1/HYAL1 Antibody [NBP2-16906] - A. 50 ug Rat liver lysate/extract 10 % SDS-PAGEHYAL1 antibody dilution: 1:1000

Immunohistochemistry-Paraffin: Hyaluronidase 1/HYAL1 Antibody [NBP2-16906] - Human endometrial carcinoma. HYAL1 stained by HYAL1 antibody diluted at 1:500.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.

Western Blot: Hyaluronidase 1/HYAL1 Antibody [NBP2-16906] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE gel, diluted at 1:1000.

• Reactivity: Hu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Hyaluronidase 1/HYAL1 Antibody - BSA Free Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human Hyaluronidase 1/HYAL1. The exact sequence is proprietary.
• Localization: Secreted; Lysosome
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HYAL1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500-1:3000
• Application Notes: IHC, IHC-P- Assay dependent
• Theoretical MW: 48 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Pig (81%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for Hyaluronidase 1/HYAL1 Antibody - BSA Free

• EC 3.2.1.35
• FUS2
• HYAL1
• HYAL-1
• Hyaluronidase 1
• Hyaluronoglucosaminidase 1
• hyaluronoglucosaminidase-1
• LUCA1
• luCa-1
• LUCA1hyaluronidase-1
• Lung carcinoma protein 1
• MGC45987
• NAT6
• plasma hyaluronidase
• tumor suppressor LUCA-1

Background

This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: HYAL1
• Uniprot:
  • Q12794()