Human TRAIL/TNFSF10 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human TRAIL/TNFSF10 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: TNFSF10

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human TRAIL/TNFSF10 DuoSet ELISA, 15 Plate

• Apo-2 ligand
• APO2L
• Apo-2Ltumor necrosis factor (ligand) family, member 10
• APO2Ltumor necrosis factor apoptosis-inducing ligand splice variant delta
• CD253 antigen
• CD253
• Protein TRAIL
• TL2
• TNF-related apoptosis-inducing ligand
• TNFSF10
• TRAIL
• TRAILTNF-related apoptosis inducing ligand TRAIL
• tumor necrosis factor (ligand) superfamily, member 10
• tumor necrosis factor ligand superfamily member 10

Background

TNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members. Among TNF superfamily members, TRAIL is the most homologous to Fas Ligand, sharing 28% amino acid sequence identity in their extracellular domains. Human TRAIL shares 65% amino acid sequence identity with mouse TRAIL and is active on mouse cells.

Publications for TRAIL/TNFSF10 (DY375)(7)

Publications using DY375

• Menevse, AN;Ammer, LM;Vollmann-Zwerenz, A;Kupczyk, M;Lorenz, J;Weidner, L;Hussein, A;Sax, J;M�hlbauer, J;Heuschneider, N;Rohrmus, C;Mai, LS;Jachnik, B;Stamova, S;Volpin, V;Durst, FC;Sorrentino, A;Xydia, M;Milenkovic, VM;Bader, S;Braun, FK;Wetzel, C;Albert, NL;Tonn, JC;Bartenstein, P;Proescholdt, M;Schmidt, NO;Linker, RA;Riemenschneider, MJ;Beckhove, P;Hau, P; TSPO acts as an immune resistance gene involved in the T cell mediated immune control of glioblastoma Acta neuropathologica communications 2023-05-08 [PMID: 37158962] (Human)
• Pan X, Pang M, Ma A, Wang K, Zhang Z, Zhong Q, Yang S Association of TRAIL and Its Receptors with Large-Artery Atherosclerotic Stroke. PLoS ONE, 2015-09-03;10(9):e0136414. 2015-09-03 [PMID: 26334877] (Human)
• Kis-Toth K, Tsokos G Engagement of SLAMF2/CD48 prolongs the time frame of effective T cell activation by supporting mature dendritic cell survival. J Immunol, 2014-03-26;192(9):4436-42. 2014-03-26 [PMID: 24670806] (Human)
• Benedict W, Fisher M, Zhang X, Yang Z, Munsell M, Dinney C Use of monitoring levels of soluble forms of cytokeratin 18 in the urine of patients with superficial bladder cancer following intravesical Ad-IFNalpha/Syn3 treatment in a phase l study. Cancer Gene Ther, 2014-02-07;21(3):91-4. 2014-02-07 [PMID: 24503570] (Human)
• Kang S, Park EJ, Joe Y, Seo E, Park MK, Seo SY, Chung HY, Yoo YH, Kim DK, Lee HJ Systemic delivery of TNF-related apoptosis-inducing ligand (TRAIL) elevates levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) and prevents type 1 diabetes in nonobese diabetic mice. Endocrinology, 2010-11-03;151(12):5638-46. 2010-11-03 [PMID: 21047948] (Mouse)
• Vermijlen D, Ellis P, Langford C, Klein A, Engel R, Willimann K, Jomaa H, Hayday AC, Eberl M Distinct cytokine-driven responses of activated blood gammadelta T cells: insights into unconventional T cell pleiotropy. J. Immunol., 2007-04-01;178(7):4304-14. 2007-04-01 [PMID: 17371987] (Human)
• Liu JM, Zhu Y, Xu ZW, Ouyang WM, Wang JP, Liu XS, Cao YX, Li Q, Fang L, Zhuang R, Yang AG, Jin BQ Dynamic changes of apoptosis-inducing ligands and Th1/Th2 like subpopulations in Hantaan virus-induced hemorrhagic fever with renal syndrome. Clin. Immunol., 2006-04-17;119(3):245-51. 2006-04-17 [PMID: 16616877] (Human)

FAQs for TRAIL/TNFSF10 (DY375). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: TNFSF10