Human Serpin E1/PAI-1 Quantikine ELISA Kit



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Reactivity HuSpecies Glossary
Applications ELISA

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Human Serpin E1/PAI-1 Quantikine ELISA Kit Summary

The Quantikine Human Serpin E1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Serpin E1 in cell culture supernates, cell lysates, and plasma. It contains Sf 21-expressed recombinant human Serpin E1 and has been shown to accurately quantitate the recombinant factor in its active and latent forms as well as in the vitronectin complexes. However, the kit does not... detect recombinant human Serpin E1 in complexes with recombinant human uPA and recombinant human tPA. Results obtained using natural human Serpin E1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Serpin E1.
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Natural and recombinant human Serpin E1
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
Interference observed with 1 or more available related molecules.
Read Publications using DSE100.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Serpin E1/PAI-1 Quantikine ELISA Kit

  • Endothelial plasminogen activator inhibitor
  • Nexin
  • PAI1
  • PAI-1
  • PAI1PAI-1
  • PAISerpin E1
  • PLANH1
  • PLANH1plasminogen activator inhibitor 1
  • serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogenactivator inhibitor type 1), member 1
  • Serpin E1
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitortype 1), member 1


The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for Serpin E1/PAI-1 (DSE100)(41)

We have publications tested in 2 confirmed species: Human, Primate - Chlorocebus aethiops (African Green Monkey).

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Primate - Chlorocebus aethiops (African Green Monkey)
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Showing Publications 1 - 10 of 41. Show All 41 Publications.
Publications using DSE100 Applications Species
AD Ruggiero, R Vemuri, M Block, D DeStephani, M Davis, J Chou, A Williams, A Brock, SK Das, K Kavanagh Macrophage Phenotypes and Gene Expression Patterns Are Unique in Naturally Occurring Metabolically Healthy Obesity International Journal of Molecular Sciences, 2022;23(20):. 2022 [PMID: 36293536] (Primate - Chlorocebus aethiops (African Green Monkey)) Primate - Chlorocebus aethiops (African Green Monkey)
BF Vahsen, E Gray, A Candalija, KML Cramb, J Scaber, R Dafinca, A Katsikoudi, Y Xu, L Farrimond, R Wade-Marti, WS James, MR Turner, SA Cowley, K Talbot Human iPSC co-culture model to investigate the interaction between microglia and motor neurons Scientific Reports, 2022;12(1):12606. 2022 [PMID: 35871163] (Human) Human
E Schapkaitz, E Libhaber, BF Jacobson, M Toman, A Gerber, HR Büller Evaluation of markers of fibrinolysis and coagulation in pregnant women with human immunodeficiency virus Thrombosis Research, 2022;217(0):1-8. 2022 [PMID: 35810616] (Human) Human
KD Wick, L Siegel, JD Neaton, C Oldmixon, J Lundgren, RL Dewar, HC Lane, BT Thompson, MA Matthay, ACTIV-3/TI RAGE has potential pathogenetic and prognostic value in nonintubated hospitalized patients with COVID-19 JCI Insight, 2022;7(9):. 2022 [PMID: 35298440] (Human) Human
Y Qin, J Zhang, S Babapoor-F, B Applewhite, M Deshpande, H Megarity, M Flores-Bel, S Aparicio-D, T Ma, Y Rui, SY Tzeng, JJ Green, MV Canto-Sole, S Montaner, A Sodhi PAI-1 is a vascular cell-specific HIF-2-dependent angiogenic factor that promotes retinal neovascularization in diabetic patients Science Advances, 2022;8(9):eabm1896. 2022 [PMID: 35235351] (Human) Human
C Cohen, O Le Goff, F Soysouvanh, F Vasseur, M Tanou, C Nguyen, L Amrouche, J Le Guen, O Saltel-Ful, T Meunier, T Nguyen-Kho, M Rabant, D Nochy, C Legendre, G Friedlande, BG Childs, DJ Baker, B Knebelmann, D Anglicheau, F Milliat, F Terzi Glomerular endothelial cell senescence drives age-related kidney disease through PAI-1 Embo Molecular Medicine, 2021;13(11):e14146. 2021 [PMID: 34725920] (Human) Human
M McAleavy, Q Zhang, PJ Ehmann, J Xu, MF Wipperman, D Ajithdoss, L Pan, M Wakai, R Simonson, A Gadi, A Oyejide, SC Hamon, A Boyapati, LG Morton, T Shavlakadz, CA Kyratsous, DJ Glass The Activin/FLRG pathway associates with poor COVID-19 outcomes in hospitalized patients Molecular and Cellular Biology, 2021;0(0):MCB0046721. 2021 [PMID: 34723652] (Human) Human
SH Cho, JH Kim, HJ An, YR Kim, EH Ahn, JR Lee, JO Kim, JJ Ko, NK Kim Genetic Polymorphisms in miR-604A>G, miR-938G>A, miR-1302-3C>T and the Risk of Idiopathic Recurrent Pregnancy Loss International Journal of Molecular Sciences, 2021;22(11):. 2021 [PMID: 34200157] (Human) Human
C Voukalis, GYH Lip, E Shantsila Effects of antithrombotic drugs on the prothrombotic state in patients with atrial fibrillation: The west Birmingham atrial fibrillation project Thrombosis Research, 2021;200(0):149-155. 2021 [PMID: 33610887] (Human) Human
YY Wang, HD Chen, S Lo, YK Chen, YC Huang, SC Hu, YC Hsieh, AC Hung, MF Hou, SF Yuan Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages Cancers, 2020;12(12):. 2020 [PMID: 33256011] (Human) Human
Show All 41 Publications.

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Gene Symbol SERPINE1