Human Reg3A DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Reg3A DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Reg3A DuoSet ELISA, 5 Plate

• hepatocarcinoma-intestine-pancreas
• HIPpancreatitis-associated protein
• Human proislet peptide
• Lithostathine 3
• pancreatic beta cell growth factor
• Pancreatitis-associated protein 1
• PAP homologous protein
• PAP1FLJ18565
• PAP2
• PAPPAP-H
• PBCGF
• proliferation-inducing protein 34
• proliferation-inducing protein 42
• Reg III-alpha
• REG3
• Reg3A
• REG-3-alpha
• regenerating islet-derived 3 alpha
• regenerating islet-derived protein 3-alpha
• Regenerating islet-derived protein III-alpha
• REG-III

Background

The Reg family constitutes a subset of the calcium-dependent C-type lectin superfamily. These small, secreted proteins have been implicated in a range of physiological processes including acting as acute phase reactants, lectins, survival/growth factors for insulin-producing pancreatic beta-cells, neural cells, and epithelial cells of the digestive system. Studies also indicate a role for Reg family members in tumor formation and indicate their potential for use as biomarkers of carcinogenesis.

Reg3A also named lithostathine 3 and pancreatitis-associated protein 2, belongs to the Regenerating gene family of C-type lectins. Reg3 is overexpressed during the acute phase of pancreatitis.

Publications for Reg3A (DY5940-05)(7)

Publications using DY5940-05

• Dokoshi, T;Chen, Y;Cavagnero, KJ;Rahman, G;Hakim, D;Brinton, S;Schwarz, H;Brown, EA;O'Neill, A;Nakamura, Y;Li, F;Salzman, NH;Knight, R;Gallo, RL; Dermal injury drives a skin to gut axis that disrupts the intestinal microbiome and intestinal immune homeostasis in mice Nature communications 2024-04-08 [PMID: 38589392] (Human)
• Boby, N;Williams, KM;Das, A;Pahar, B; Toll-like Receptor 2 Mediated Immune Regulation in Simian Immunodeficiency Virus-Infected Rhesus Macaques Vaccines 2023-12-17 [PMID: 38140264] (Primate - Macaca mulatta (Rhesus Macaque))
• Planchais, C;Molinos-Albert, LM;Rosenbaum, P;Hieu, T;Kanyavuz, A;Clermont, D;Prazuck, T;Lefrou, L;Dimitrov, JD;Hüe, S;Hocqueloux, L;Mouquet, H; HIV-1 treatment timing shapes the human intestinal memory B-cell repertoire to commensal bacteria Nature communications 2023-10-10 [PMID: 37816704] (Human)
• Mboumba Bouassa, R;Comeau, E;Alexandrova, Y;Pagliuzza, A;Yero, A;Samarani, S;Needham, J;Singer, J;Lee, T;Bobeuf, F;Vertzagias, C;Sebastiani, G;Margolese, S;Mandarino, E;Klein, M;Lebouché, B;Routy, J;Chomont, N;Costiniuk, C;Jenabian, M; Effects of Oral Cannabinoids on Systemic Inflammation and Viral Reservoir Markers in People with HIV on Antiretroviral Therapy: Results of the CTN PT028 Pilot Clinical Trial Cells 2023-01-01 [PMID: 37508476] (Human)
• KK Jang, T Heaney, M London, Y Ding, F Yeung, D Ercelen, YH Chen, J Axelrad, S Gurunathan, A Marijke Ke, ME Griffin, HC Hang, K Cadwell Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization bioRxiv : the preprint server for biology, 2023-02-01;0(0):. 2023-02-01 [PMID: 36778381] (Human)
• X Ding, S Liu, S Zhu, B Zhou, H Ma A Pilot Study on Human Circulating System Indicated That Regenerating Islet-Derived Protein 3 Gamma (REG3A) is a Potential Prognostic Biomarker for Sepsis The American journal of cardiology, 2022-12-24;190(0):90-95. 2022-12-24 [PMID: 36571936] (Human)
• N Zhang, Y Gou, S Liang, N Chen, Y Liu, Q He, J Zhang Dysbiosis of Gut Microbiota Promotes Hepatocellular Carcinoma Progression by Regulating the Immune Response Journal of Immunology Research, 2021-10-20;2021(0):4973589. 2021-10-20 [PMID: 34722779] (Human)

FAQs for Reg3A (DY5940-05). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.