Human IL-6 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human IL-6 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: IL6

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-6 DuoSet ELISA, 15 Plate

• B-cell differentiation factor
• B-cell stimulatory factor 2
• BSF2
• BSF-2
• CDF
• CTL differentiation factor
• HSF
• hybridoma growth factor
• IFNB2
• IFN-beta-2
• IL6
• IL-6
• Interferon beta-2
• interleukin 6 (interferon, beta 2)
• interleukin BSF-2
• interleukin-6
• MGI-2A

Background

Interleukin 6 (IL-6) is a pleiotropic, a-helical, 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. Mature human IL-6 is 183 amino acids (aa) in length and shares 39% aa sequence identity with mouse and rat IL-6. Alternative splicing generates several isoforms with internal deletions, some of which exhibit antagonistic properties. Cells known to express IL-6 include CD8+ T cells, fibroblasts, synoviocytes, adipocytes, osteoblasts, megakaryocytes, endothelial cells (under the influence of endothelins), sympathetic neurons, cerebral cortex neurons, adrenal medulla chromaffin cells, retinal pigment cells, mast cells, keratinocytes, Langerhans cells, fetal and adult astrocytes, neutrophils, monocytes, eosinophils, colonic epithelial cells, B1 B cells and pancreatic islet beta cells. IL-6 production is generally correlated with cell activation and is normally kept in control by glucocorticoids, catecholamines, and secondary sex steroids. Normal human circulating IL-6 is in the 1 pg/mL range, with slight elevations during the menstrual cycle, modest elevations in certain cancers, and large elevations after surgery.

IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R alpha) and a signal transducing subunit (gp130). IL-6 binds to IL-6 Ra, triggering IL-6 Ra association with gp130 and gp130 dimerization. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 Ra are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 Ra elicit responses from gp130-expressing cells that lack cell surface IL-6 Ra. Trans-signaling enables a wider range of cell types to respond to IL-6, as the expression of gp130 is ubiquitous, while that of IL-6 Ra is predominantly restricted to hepatocytes, monocytes, and resting lymphocytes. Soluble splice forms of gp130 block trans-signaling from IL-6/IL-6 Ra but not from other cytokines that use gp130 as a co-receptor. 

IL-6, along with TNF-a and IL-1, drives the acute inflammatory response. IL-6 is almost solely responsible for fever and the acute phase response in the liver, and it is important in the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. When dysregulated, it contributes to chronic inflammation in conditions such as obesity, insulin resistance, inflammatory bowel disease, arthritis, and sepsis. IL-6 modulates bone resorption and is a major effector of inflammatory joint destruction in rheumatoid arthritis through its promotion of Th17 cell development and activity. It contributes to atherosclerotic plaque development and destabilization as well as the development of inflammation-associated carcinogenesis.

Publications for IL-6 (DY206)(611)

Publications using DY206

• Nowotny, HF;Choi, H;Ziegler, S;Doll, N;Bäuerle, A;Welp, AC;Dubinski, I;Schiergens, K;Neumann, U;Tschaidse, L;Auer, MK;Rothenfusser, S;Schmidt, H;Reisch, N; Immunophenotypic Implications of Reverse-Circadian Glucocorticoid Treatment in Congenital Adrenal Hyperplasia International journal of molecular sciences 2025-02-10 [PMID: 40003944] (Human)
• Li, M;Xie, H;Du, X; Cystatin C 3 (CST3) drives pathological progression in recurrent spontaneous abortion Journal of reproductive immunology 2025-01-21 [PMID: 39914057] (Mouse)
• Coughlin, CA;Chahar, D;Lekakis, M;Youssfi, AA;Li, L;Roberts, E;Gallego, NC;Volmar, CH;Landgren, O;Brothers, S;Griswold, AJ;Amador, C;Bilbao, D;Maura, F;Schatz, JH; Bruton's tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax Blood cancer journal 2025-02-02 [PMID: 39894894] (Human)
• Parau, AC;Büyüksungur, S;Li, G;Liu, Q;Badillo, E;Blum, L;Schmidt, J;Pana, I;Vitelaru, C;Marinescu, IM;Dinu, M;Smuglov, M;Schmuttermaier, C;Tanir, TE;Klüter, H;Hasirci, N;Kzhyshkowska, J;Dragomir, AV; Zn-doped CaP coating equips Ti implants with corrosion resistance, biomineralization, antibacterial and immunotolerant activities Journal of advanced research 2025-01-27 [PMID: 39880075] (Human)
• Chai, N;Stachon, T;Häcker, S;Berger, T;Li, Z;Amini, M;Suiwal, S;Seitz, B;Langenbucher, A;Szentmáry, N; The cellular response of lipopolysaccharide-induced inflammation in keratoconus human corneal fibroblasts to RB-PDT: Insights into cytokines, chemokines and related signaling pathways PloS one 2025-01-27 [PMID: 39869570] (Human)
• Bettinsoli, V;Melzi, G;Crea, A;Esposti, L;Iafisco, M;Catalucci, D;Ciana, P;Corsini, E; A Novel Approach for In Vitro Testing and Hazard Evaluation of Nanoformulated RyR2-Targeting siRNA Drugs Using Human PBMCs Life 2025-01-14 [PMID: 39860035] (Human)
• Navas, A;Matzaraki, V;van Eekeren, LE;Blaauw, MJT;Groenendijk, AL;Vos, WAJW;Jacobs-Cleophas, M;Dos Santos, JC;van der Ven, AJAM;Joosten, LAB;Netea, MG; Plasma Proteomic Signature as a Predictor of Age Advancement in People Living With HIV Aging cell 2025-01-15 [PMID: 39812213] (Human)
• Zima, K;Sochocka, M;Ochnik, M;Khaidakov, B;Lemke, K;Kowalczyk, P; Therapeutic Potential of a Natural Blend of Aronia melancarpa, Lonicera caerulea, and Echinacea purpurea Extracts in Treating Upper Respiratory Tract Infections: Preliminary Clinical and In Vitro Immunomodulatory Insights International journal of molecular sciences 2024-12-15 [PMID: 39769201] (Human)
• Pourfarzam, S;Ardestani, SK;Jamali, T;Ghazanfari, H;Naghizadeh, MM;Faghihzadeh, S;Yaraee, R;Ghazanfari, Z;Ghazanfari, T; Distinct inflammatory profiles in mustard lung: A study of sulfur mustard-exposed patients with serious pulmonary complications International immunopharmacology 2024-12-16 [PMID: 39689604] (Human)
• Tucker, RM;Kim, N;Gurzell, E;Mathi, S;Chavva, S;Senthilkumar, D;Bartunek, O;Fenton, KC;Herndon-Fenton, SJ;Cardino, VN;Cooney, GM;Young, S;Fenton, JI; Commonly Used Dose of Montmorency Tart Cherry Powder Does Not Improve Sleep or Inflammation Outcomes in Individuals with Overweight or Obesity Nutrients 2024-11-28 [PMID: 39683518] (Human)
• Kumar, N;Mattoo, SS;Sanghvi, S;Ellendula, MP;Mahajan, S;Planner, C;Bednash, JS;Khan, M;Ganesan, LP;Singh, H;Lafuse, WP;Wozniak, DJ;Rajaram, MVS; Pseudomonas aeruginosa- mediated cardiac dysfunction is driven by extracellular vesicles released during infection bioRxiv : the preprint server for biology 2024-11-25 [PMID: 39651123] (Human)
• Bekirian, C;Valsecchi, I;Bachellier-Bassi, S;Scandola, C;Guijarro, JI;Chauvel, M;Mourer, T;Gow, NAR;Aimanianda, VK;d'Enfert, C;Fontaine, T; ?-1,6-Glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall eLife 2024-12-05 [PMID: 39636210] (Human)
• Gerasimova, EV;Popkova, TV;Kirillova, IG;Gerasimova, DA;Nasonov, EL;Lila, AM; Interleukin-6: Cardiovascular Aspects of Long-Term Cytokine Suppression in Patients with Rheumatoid Arthritis International journal of molecular sciences 2024-11-19 [PMID: 39596487] (Human)
• Bousch, JF;Beyersdorf, C;Schultz, K;Windolf, J;Suschek, CV;Maus, U; Proinflammatory Cytokines Enhance the Mineralization, Proliferation, and Metabolic Activity of Primary Human Osteoblast-like Cells International journal of molecular sciences 2024-11-18 [PMID: 39596421] (Human)
• Snuggs, JW;Senter, RK;Whitt, JP;Jackson, JD;Le Maitre, CL; PCRX-201, a novel IL-1Ra gene therapy treatment approach for low back pain resulting from intervertebral disc degeneration Gene therapy 2024-11-21 [PMID: 39572769] (Human)
• Seo, SM;Kim, NW;Yoo, ES;Lee, JH;Kang, AR;Jeong, HB;Shim, WY;Kim, DH;Park, YJ;Bae, K;Yoon, KA;Choi, YK; Development of a novel complex inflammatory bowel disease mouse model: Reproducing human inflammatory bowel disease etiologies in mice PloS one 2024-11-21 [PMID: 39570897] (Mouse)
• Arianti, R;Vinnai, BÁ;Alrifai, R;Karadsheh, G;Al-Khafaji, YQ;Póliska, S;Gy?ry, F;Fésüs, L;Kristóf, E; Upregulation of inhibitor of DNA binding 1 and 3 is important for efficient thermogenic response in human adipocytes Scientific reports 2024-11-16 [PMID: 39550428] (Human)
• Duijzer, R;Dalloyaux, D;Boerrigter, MM;Lemmers, H;Dijkstra, H;van Emst, L;Te Morsche, RHM;Jaeger, M;Joosten, LAB;Drenth, JPH; Exploring the innate immune response in polycystic liver disease Cytokine 2024-12-01 [PMID: 39541862] (Human)
• Moura-Maia, MS;Brill, B;Paula-Vieira, RHR;Ramos-Gomes, NV;Melamed, D;Silva-Reis, A;Wolpp, ETR;Moreira-Silva, NN;Bella, YF;Vieira, RP; Low Caloric Intake Confers Cardiovascular Protection and Improves Functional Capacity Without Affecting Immunological Response in Sedentary Older Adults Nutrients 2024-10-29 [PMID: 39519510] (Human)
• Shepelkova, GS;Evstifeev, VV;Berezovskiy, YS;Ergeshova, AE;Tarasov, RV;Bagirov, MA;Yeremeev, VV; Characteristics of Pulmonary Inflammation in Patients with Different Forms of Active Tuberculosis International journal of molecular sciences 2024-11-02 [PMID: 39519346] (Human)
• Vargas-Castro, R;García-Quiroz, J;Olmos-Ortiz, A;Avila, E;Larrea, F;Díaz, L; Calcitriol prevents SARS-CoV spike-induced inflammation in human trophoblasts through downregulating ACE2 and TMPRSS2 expression The Journal of steroid biochemistry and molecular biology 2025-01-01 [PMID: 39515592] (Human)
• Flores-Gomez, D;Hobo, W;van Ens, D;Kessler, EL;Novakovic, B;Schaap, NPM;Rijnen, WHC;Joosten, LAB;Netea, MG;Riksen, NP;Bekkering, S; Interleukin-1? induces trained innate immunity in human hematopoietic progenitor cells in vitro Stem cell reports 2024-09-25 [PMID: 39515317] (Human)
• Bodrova, VV;Shustova, ON;Golubeva, NV;Alieva, AK;Vlodzyanovsky, VV;Pevzner, DV;Mazurov, AV; Platelet Function, Platelet Size and Content of Reticulated Platelets: Interactions in Patients Receiving Dual Antiplatelet Therapy Cells 2024-10-16 [PMID: 39451230] (Human)
• Riel, AMS;Rungelrath, V;Elwaie, TA;Rasheed, OK;Hicks, L;Ettenger, G;You, DC;Smith, M;Buhl, C;Abdelwahab, W;Miller, SM;Smith, AJ;Burkhart, D;Evans, JT;Ryter, KT; Systematic Evaluation of Regiochemistry and Lipidation of Aryl Trehalose Mincle Agonists International journal of molecular sciences 2024-09-18 [PMID: 39337517] (Human)
• Hampton, TH;Barnaby, R;Roche, C;Nymon, A;Fukutani, KF;MacKenzie, TA;Stanton, BA; Gene expression responses of CF airway epithelial cells exposed to elexacaftor/tezacaftor/ivacaftor (ETI) suggest benefits beyond improved CFTR channel function bioRxiv : the preprint server for biology 2024-08-29 [PMID: 39257747] (Human)
• Maruthupandy, M;Jeon, JH;Noh, J;Yang, SI;Cho, WS; Mitigated toxicity of polystyrene nanoplastics in combination exposure with copper ions by transformation into copper (I) oxide: Inhibits the oxidative potential of nanoplastics Chemosphere 2024-09-05 [PMID: 39243901] (Human)
• Yadav, P;Ortega, JG;Tamaki, W;Chien, C;Chang, KC;Biswas, N;Pan, S;Nilsson, J;Yin, X;Bhattacharyya, A;Boostanpour, K;Jujaray, T;Wang, J;Tsukui, T;Sheppard, D;Li, B;Maishan, M;Taenaka, H;Matthay, MA;Muramatsu, R;Maliskova, L;Ghosh, A;Eckalbar, WL;Molofsky, AB;Wolters, PJ;Tamaki, SJ;Bivona, T;Abate, AR;Wagner, A;Tharp, KM;Bhattacharya, M; Macrophage-fibroblast crosstalk drives Arg1-dependent lung fibrosis via ornithine loading bioRxiv : the preprint server for biology 2024-07-31 [PMID: 39211079] (Human)
• Tan, KBC;Alexander, HD;Linden, J;Murray, EK;Gibson, DS; Anti-inflammatory effects of phytocannabinoids and terpenes on inflamed Tregs and Th17 cells in vitro Experimental and molecular pathology 2024-08-28 [PMID: 39208564] (Human)
• Soko?owska, P;Wiktorowska-Owczarek, A;Tambor, J;Gawlak-Socka, S;Kowalczyk, E;Jó?wiak-B?benista, M; Endoplasmic Reticulum Stress Differently Modulates the Release of IL-6 and IL-8 Cytokines in Human Glial Cells International journal of molecular sciences 2024-08-09 [PMID: 39201378] (Human)
• Jacobs, MME;Maas, RJF;Jonkman, I;Negishi, Y;Tielemans Zamora, W;Yanginlar, C;van Heck, J;Matzaraki, V;Martens, JHA;Baltissen, M;Vermeulen, M;Morla-Folch, J;Ranzenigo, A;Wang, W;Umali, M;Ochando, J;van der Vlag, J;Hilbrands, LB;Joosten, LAB;Netea, MG;Mulder, WJM;van Leent, MMT;Mhlanga, MM;Teunissen, AJP;Rother, N;Duivenvoorden, R; Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling Cell reports 2024-08-22 [PMID: 39178113] (Human)
• Zima, K;Khaidakov, B;Sochocka, M;Ochnik, M;Lemke, K;Kowalczyk, P; Exploring the potency of polyphenol-rich blend from Lonicera caerulea var. Kamtschatica sevast., Aronia melanocarpa, and Echinacea purpurea: Promising anti-inflammatory, antioxidant, and antiviral properties Heliyon 2024-08-15 [PMID: 39170264] (Human)
• Marzagalli, M;Battaglia, S;Raimondi, M;Fontana, F;Cozzi, M;Ranieri, FR;Sacchi, R;Curti, V;Limonta, P; Anti-Inflammatory and Antioxidant Properties of a New Mixture of Vitamin C, Collagen Peptides, Resveratrol, and Astaxanthin in Tenocytes: Molecular Basis for Future Applications in Tendinopathies Mediators of inflammation 2024-07-30 [PMID: 39108992] (Human)
• McPhail, DK;Alzahrani, MAM;Martin, KR;Calver, BL;Harwood, AJ;MacKeigan, JP;Davies, DM;Tee, AR; Loss of Tuberous Sclerosis Complex 2 confers inflammation via dysregulation of Nuclear factor kappa-light-chain-enhancer of activated B cells Research square 2024-07-15 [PMID: 39070657] (Human)
• Cab?u, G;Badii, M;Mirea, AM;Gaal, OI;van Emst, L;Popp, RA;Cri?an, TO;Joosten, LAB; Long-Lasting Enhanced Cytokine Responses Following SARS-CoV-2 BNT162b2 mRNA Vaccination Vaccines 2024-07-03 [PMID: 39066374] (Human)
• Kim, TJ;MacElroy, AS;Defreitas, A;Shenker, BJ;Boesze-Battaglia, K; A Synthetic Small Molecule, LGM2605: A Promising Modulator of Increased Pro-Inflammatory Cytokine and Osteoclast Differentiation by Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Dentistry journal 2024-06-26 [PMID: 39056982] (Human)
• Nasr, MA;Aldous, A;Daniels, J;Joy, C;Capozzi, E;Yang, M;Moriarty, P;Emmanuel-Baker, V;Malcolm, S;Green, SJ;Gomez-Lobo, V;Ghosh, M; Effect of progestin-based contraceptives on HIV-associated vaginal immune biomarkers and microbiome in adolescent girls PloS one 2024-07-15 [PMID: 39008499] (Human)
• Cherpaz, M;Meugnier, E;Seillier, G;Pozzi, M;Pierrard, R;Leboube, S;Farhat, F;Vola, M;Obadia, JF;Amaz, C;Chalabreysse, L;May, C;Chanon, S;Brun, C;Givre, L;Bidaux, G;Mewton, N;Derumeaux, G;Bergerot, C;Paillard, M;Thibault, H; Myocardial transcriptomic analysis of diabetic patients with aortic stenosis: key role for mitochondrial calcium signaling Cardiovascular diabetology 2024-07-08 [PMID: 38978010] (Human)
• Cho, HY;Lee, JE;Park, KH;Choi, BY;Lee, MJ;Jeong, DE;Shin, S; Identification and characterization of plasma proteins associated with intra-amniotic inflammation and/or infection in women with preterm labor. Scientific reports 2024-06-25 [PMID: 38918423] (Human)
• Carneiro Junior, WO;Guimarães, MLR;Freitas, KM;Pereira, RS;Pádua, RM;Campana, PRV;Braga, FC; Structural characterization of a proanthocyanidin-rich fraction from Hancornia speciosa leaves and its effect on the release of pro-inflammatory cytokines and oxidative stress in THP-1 cells Journal of ethnopharmacology 2024-06-18 [PMID: 38901680] (Human)
• Dobrea, A;Hall, N;Milne, S;Corrigan, DK;Jimenez, M; A plug-and-play, easy-to-manufacture fluidic accessory to significantly enhance the sensitivity of electrochemical immunoassays Scientific reports 2024-06-19 [PMID: 38898088] (Human, N/A)
• Louault, K;Blavier, L;Lee, MH;Kennedy, RJ;Fernandez, GE;Pawel, BR;Asgharzadeh, S;DeClerck, YA; Nuclear factor-?B activation by transforming growth factor-?1 drives tumour microenvironment-mediated drug resistance in neuroblastoma British journal of cancer 2024-05-28 [PMID: 38806726] (Human)
• Kurmasheva, N;Said, A;Wong, B;Kinderman, P;Han, X;Rahimic, AHF;Kress, A;Carter-Timofte, ME;Holm, E;van der Horst, D;Kollmann, CF;Liu, Z;Wang, C;Hoang, HD;Kovalenko, E;Chrysopoulou, M;Twayana, KS;Ottosen, RN;Svenningsen, EB;Begnini, F;Kiib, AE;Kromm, FEH;Weiss, HJ;Di Carlo, D;Muscolini, M;Higgins, M;van der Heijden, M;Bardoul, A;Tong, T;Ozsvar, A;Hou, WH;Schack, VR;Holm, CK;Zheng, Y;Ruzek, M;Kalucka, J;de la Vega, L;Elgaher, WAM;Korshoej, AR;Lin, R;Hiscott, J;Poulsen, TB;O'Neill, LA;Roy, DG;Rinschen, MM;van Montfoort, N;Diallo, JS;Farin, HF;Alain, T;Olagnier, D; Octyl itaconate enhances VSV?51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways Nature communications 2024-05-15 [PMID: 38750019] (Human)
• Marinho, A;Seabra, CL;Lima, SAC;Lobo-da-Cunha, A;Reis, S;Nunes, C; Empowering Naringin's Anti-Inflammatory Effects through Nanoencapsulation International journal of molecular sciences 2024-04-09 [PMID: 38673736] (Human)
• Chick, HM;Rees, ME;Lewis, ML;Williams, LK;Bodger, O;Harris, LG;Rushton, S;Wilkinson, TS; Using the Traditional Ex Vivo Whole Blood Model to Discriminate Bacteria by Their Inducible Host Responses Biomedicines 2024-03-25 [PMID: 38672079] (Human)
• Finegood, ED;Weissman-Tsukamoto, R;Lam, P;Chen, E;Miller, GE; Interpersonal violence exposure and inflammation during adolescence and young adulthood Psychoneuroendocrinology 2024-03-11 [PMID: 38518706] (Human)
• Campanari, D;Rosa, U;Fraga?Silva, T;Ramalho, L;Ovídio, P;Júnior, A;Bonato, V;Ferriolli, E; Effect of Dietary Supplementation with Omega-3 Fatty Acid on the Generation of Regulatory T Lymphocytes and on Antioxidant Parameters and Markers of Oxidative Stress in the Liver Tissue of IL?10 Knockout Mice Nutrients 2024-02-24 [PMID: 38474762] (Mouse)
• Assis, SIS;Amendola, LS;Okamoto, MM;Ferreira, GDS;Iborra, RT;Santos, DR;Santana, MFM;Santana, KG;Correa-Giannella, ML;Barbeiro, DF;Soriano, FG;Machado, UF;Passarelli, M; The Prolonged Activation of the p65 Subunit of the NF-Kappa-B Nuclear Factor Sustains the Persistent Effect of Advanced Glycation End Products on Inflammatory Sensitization in Macrophages International journal of molecular sciences 2024-02-27 [PMID: 38473959] (Human)
• Dos Santos, JC;Moreno, M;Teufel, LU;Chilibroste, S;Keating, ST;Groh, L;Domínguez-Andrés, J;Williams, DL;Ma, Z;Lowman, DW;Ensley, HE;Novakovic, B;Ribeiro-Dias, F;Netea, MG;Chabalgoity, JA;Joosten, LAB; Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity Cell reports 2024-03-07 [PMID: 38457336] (Human)
• Li, Y;Nie, Y;Yang, X;Liu, Y;Deng, X;Hayashi, Y;Plummer, R;Li, Q;Luo, N;Kasai, T;Okumura, T;Kamishibahara, Y;Komoto, T;Ohkuma, T;Okamoto, S;Isobe, Y;Yamaguchi, K;Furukawa, Y;Taniguchi, H; Integration of Kupffer cells into human iPSC-derived liver organoids for modeling liver dysfunction in sepsis Cell reports 2024-03-05 [PMID: 38451817] (Human)
• Tuchscherr, L;Wendler, S;Santhanam, R;Priese, J;Reissig, A;Müller, E;Ali, R;Müller, S;Löffler, B;Monecke, S;Ehricht, R;Guntinas-Lichius, O; Reduced Glycolysis and Cytotoxicity in Staphylococcus aureus Isolates from Chronic Rhinosinusitis as Strategies for Host Adaptation International journal of molecular sciences 2024-02-13 [PMID: 38396905] (Human)
• Ray, I;Möller-Levet, CS;Michael, A;Butler-Manuel, S;Chatterjee, J;Tailor, A;Ellis, PE;Meira, LB; Circulating Adipocytokines and Insulin Like-Growth Factors and Their Modulation in Obesity-Associated Endometrial Cancer Cancers 2024-01-26 [PMID: 38339282] (Human)
• Vicariotto, F;Malfa, P;Viciani, E;Dell'Atti, F;Squarzanti, DF;Marcante, A;Castagnetti, A;Ponchia, R;Governini, L;De Leo, V; Efficacy of Lactiplantibacillus plantarum PBS067, Bifidobacterium animalis subsp. lactis BL050, and Lacticaseibacillus rhamnosus LRH020 in the Amelioration of Vaginal Microbiota in Post-Menopausal Women: A Prospective Observational Clinical Trial Nutrients 2024-01-30 [PMID: 38337685] (Human)
• Zhang, Y;Bharathi, V;Dokoshi, T;de Anda, J;Ursery, LT;Kulkarni, NN;Nakamura, Y;Chen, J;Luo, EWC;Wang, L;Xu, H;Coady, A;Zurich, R;Lee, MW;Matsui, T;Lee, H;Chan, LC;Schepmoes, AA;Lipton, MS;Zhao, R;Adkins, JN;Clair, GC;Thurlow, LR;Schisler, JC;Wolfgang, MC;Hagan, RS;Yeaman, MR;Weiss, TM;Chen, X;Li, MMH;Nizet, V;Antoniak, S;Mackman, N;Gallo, RL;Wong, GCL; Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes Proceedings of the National Academy of Sciences of the United States of America 2024-02-06 [PMID: 38306481] (Human)
• Mestriner, F;Francisco, DF;Campos, LCB;Couto, AES;Fraga-Silva, TFC;Flora Dugaich, V;D Avila-Mesquita, C;Zukowski Kovacs, H;Vasconcelos, JL;Milani, ER;Santos Guedes de Sá, K;Martins, R;Jordani, MC;Corsi, CAC;Barbosa, JM;Vasconcelos, T;Gonçalves Menegueti, M;Neto, J;da Costa, RM;Evora, PRB;Arruda, E;Tostes, R;Polonis, K;Bonato, VLD;Auxiliadora-Martins, M;Ribeiro, MS;Becari, C; Alpha 1-acid glycoprotein is upregulated in severe COVID-19 patients and decreases neutrophil NETs in SARS-CoV-2 infection Cytokine 2024-01-31 [PMID: 38301358] (Human)
• Bo?kun, ?;Starosz, A;Kr?towska-Grunwald, A;Wasiluk, T;Walewska, A;Wierzbowska, A;Moniuszko, M;Grubczak, K; Effects of Combinatory In Vitro Treatment with Immune Checkpoint Inhibitors and Cytarabine on the Anti-Cancer Immune Microenvironment in De Novo AML Patients Cancers 2024-01-22 [PMID: 38275902] (Human)
• Macrì, F;Vigorito, I;Castiglione, S;Faggiano, S;Casaburo, M;Fanotti, N;Piacentini, L;Vigetti, D;Vinci, MC;Raucci, A; High Phosphate-Induced JAK-STAT Signalling Sustains Vascular Smooth Muscle Cell Inflammation and Limits Calcification Biomolecules 2023-12-24 [PMID: 38254629] (Human)
• Ozmen, A;Nwabuobi, C;Tang, Z;Guo, X;Larsen, K;Guller, S;Blas, J;Moore, M;Kayisli, UA;Lockwood, CJ;Guzeloglu-Kayisli, O; Leptin-Mediated Induction of IL-6 Expression in Hofbauer Cells Contributes to Preeclampsia Pathogenesis International journal of molecular sciences 2023-12-21 [PMID: 38203306] (Human)
• Mahamed, Z;Shadab, M;Najar, RA;Millar, MW;Bal, J;Pressley, T;Fazal, F; The Protective Role of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Protein Sigma-1 Receptor in Regulating Endothelial Inflammation and Permeability Associated with Acute Lung Injury Cells 2023-12-19 [PMID: 38201208] (Human)
• Kelly, E;Lindberg, K;Jones-Isaac, K;Yang, J;Bain, J;Wang, L;MacDonald, J;Bammler, T;Calamia, J;Thummel, K;Yeung, C;Countryman, S;Koenig, P;Himmelfarb, J; Impact of microgravity on a three-dimensional microphysiologic culture of the human kidney proximal tubule epithelium: cell response to serum and vitamin D Research square 2023-12-21 [PMID: 38196580] (Human)
• Kuçi, Z;Piede, N;Vogelsang, K;Pfeffermann, LM;Wehner, S;Salzmann-Manrique, E;Stais, M;Kreyenberg, H;Bonig, H;Bader, P;Kuçi, S; Expression of HLA-DR by mesenchymal stromal cells in the platelet lysate era: an obsolete release criterion for MSCs? Journal of translational medicine 2024-01-09 [PMID: 38195462] (Human)
• Sullivan, MA;Lane, SD;McKenzie, ADJ;Ball, SR;Sunde, M;Neely, GG;Moreno, CL;Maximova, A;Werry, EL;Kassiou, M; iPSC-derived PSEN2 (N141I) astrocytes and microglia exhibit a primed inflammatory phenotype Journal of neuroinflammation 2024-01-04 [PMID: 38178159] (Human)
• Kim, YT;Huh, JW;Choi, YH;Yoon, HK;Nguyen, TT;Chun, E;Jeong, G;Park, S;Ahn, S;Lee, WK;Noh, YW;Lee, KS;Ahn, HS;Lee, C;Lee, SM;Kim, KS;Suh, GJ;Jeon, K;Kim, S;Jin, M; Highly secreted tryptophanyl tRNA synthetase 1 as a potential theranostic target for hypercytokinemic severe sepsis EMBO molecular medicine 2024-01-01 [PMID: 38177528] (Mouse)
• Räth, U;Mester, P;Schwarz, H;Schmid, S;Müller, M;Buechler, C;Pavel, V; Soluble CD137: A Potential Prognostic Biomarker in Critically Ill Patients International journal of molecular sciences 2023-12-15 [PMID: 38139346] (Human)
• Lee, KS;Kim, Y;Lee, JH;Shon, S;Kim, A;Pham, AVQ;Kim, C;Kim, DH;Kim, YK;Cho, EG; Human Probiotic Lactobacillus paracasei-Derived Extracellular Vesicles Improve Tumor Necrosis Factor-?-Induced Inflammatory Phenotypes in Human Skin Cells 2023-12-07 [PMID: 38132109] (Human)
• Wu, WC;Shiu, C;Tong, TK;Leung, SO;Hui, CW; Suppression of NK Cell Activation by JAK3 Inhibition: Implication in the Treatment of Autoimmune Diseases Journal of immunology research 2023-12-08 [PMID: 38106519] (Human)
• Kim, HS;Kim, HJ;Hong, YD;Son, ED;Cho, SY; ?-endorphin suppresses ultraviolet B irradiation-induced epidermal barrier damage by regulating inflammation-dependent mTORC1 signaling Scientific reports 2023-12-15 [PMID: 38102220] (Human)
• de Sousa, DC;Sobreira, EST;Feitosa, WLQ;Aires, TMPM;Araújo, LPP;Silva, ALC;Joventino, CB;Silveira, NMT;Chaves-Filho, AJM;Macêdo, DS;Braga-Neto, P; Cognitive dysfunction in systemic lupus erythematosus is associated with disease activity and oxidative stress: a comparative study with rheumatoid arthritis for identifying biomarkers BMC neuroscience 2023-12-13 [PMID: 38093175] (Human)
• Elhai, M;Micheroli, R;Houtman, M;Mirrahimi, M;Moser, L;Pauli, C;Bürki, K;Laimbacher, A;Kania, G;Klein, K;Schätzle, P;Bertoncelj, MF;Edalat, SG;Keusch, L;Khmelevskaya, A;Toitou, M;Geiss, C;Rauer, T;Sakkou, M;Kollias, G;Armaka, M;Distler, O;Ospelt, C; The long non-coding RNA HOTAIR contributes to joint-specific gene expression in rheumatoid arthritis Nature communications 2023-12-09 [PMID: 38071204] (Human)
• Sivaraman, K;Pino, P;Raussin, G;Anchisi, S;Metayer, C;Dagany, N;Held, J;Wrenger, S;Welte, T;Wurm, MJ;Wurm, FM;Olejnicka, B;Janciauskiene, S; Human PBMCs Form Lipid Droplets in Response to Spike Proteins Microorganisms 2023-11-01 [PMID: 38004695] (Human)
• Cholon, DM;Greenwald, MA;Higgs, MG;Quinney, NL;Boyles, SE;Meinig, SL;Minges, JT;Chaubal, A;Tarran, R;Ribeiro, CMP;Wolfgang, MC;Gentzsch, M; A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent Pseudomonas aeruginosa Infection Cells 2023-11-13 [PMID: 37998353] (Human)
• Rother, N;Yanginlar, C;Prévot, G;Jonkman, I;Jacobs, M;van Leent, MMT;van Heck, J;Matzaraki, V;Azzun, A;Morla-Folch, J;Ranzenigo, A;Wang, W;van der Meel, R;Fayad, ZA;Riksen, NP;Hilbrands, LB;Lindeboom, RGH;Martens, JHA;Vermeulen, M;Joosten, LAB;Netea, MG;Mulder, WJM;van der Vlag, J;Teunissen, AJP;Duivenvoorden, R; Acid ceramidase regulates innate immune memory Cell reports 2023-11-22 [PMID: 37995184] (Human)
• Kingkaew, E;Woraprayote, W;Booncharoen, A;Niwasabutra, K;Janyaphisan, T;Vilaichone, RK;Yamaoka, Y;Visessanguan, W;Tanasupawat, S; Functional genome analysis and anti-Helicobacter pylori activity of a novel bacteriocinogenic Lactococcus sp. NH2-7C from Thai fermented pork (Nham) Scientific reports 2023-11-21 [PMID: 37990119] (Human)
• Sereti, I;Verburgh, ML;Gifford, J;Lo, A;Boyd, A;Verheij, E;Verhoeven, A;Wit, FWNM;Schim van der Loeff, MF;Giera, M;Kootstra, NA;Reiss, P;Vujkovic-Cvijin, I; Impaired gut microbiota-mediated short-chain fatty acid production precedes morbidity and mortality in people with HIV Cell reports 2023-10-30 [PMID: 37918403] (Human)
• Gysan, MR;Milacek, C;Bal, C;Zech, A;Brugger, J;Milos, RI;Antoniewicz, L;Idzko, M;Gompelmann, D; Ventilatory support and inflammatory peptides in hospitalised patients with COVID-19: A prospective cohort trial PloS one 2023-11-02 [PMID: 37917760] (Human)
• Campesi, I;Capobianco, G;Cano, A;Lodde, V;Cruciani, S;Maioli, M;Sotgiu, G;Idda, ML;Puci, MV;Ruoppolo, M;Costanzo, M;Caterino, M;Cambosu, F;Montella, A;Franconi, F; Stratification of Amniotic Fluid Cells and Amniotic Fluid by Sex Opens Up New Perspectives on Fetal Health Biomedicines 2023-10-18 [PMID: 37893203] (Human)
• Ellefsen, CF;Lindstad, L;Klau, LJ;Aachmann, FL;Hiorth, M;Samuelsen, ABC; Investigation of the structural and immunomodulatory properties of alkali-soluble ?-glucans from Pleurotus eryngii fruiting bodies Carbohydrate polymers 2023-12-15 [PMID: 37839837] (Human)
• Chung, IC;Huang, WC;Huang, YT;Chen, ML;Tsai, AW;Wu, PY;Yuan, TT; Unrevealed roles of extracellular enolase?1 (ENO1) in promoting glycolysis and pro?cancer activities in multiple myeloma via hypoxia?inducible factor 1? Oncology reports 2023-11-01 [PMID: 37800625] (Human, Mouse)
• Flores Gomez, D;Bekkering, S;Horst, RT;Cossins, B;van den Munckhof, ICL;Rutten, JHW;Joosten, LAB;Netea, MG;Riksen, NP; The effect of leptin on trained innate immunity and on systemic inflammation in subjects with obesity Journal of leukocyte biology 2023-09-30 [PMID: 37776323] (Human)
• Kaneki, M;Ohira, C;Takahashi, M;Iwashita, N;Takagi, Y;Nagane, M;Uchiyama, J;Fukuyama, T; Therapeutic potential of ozone water treatment in alleviating atopic dermatitis symptoms in mouse models: Exploring its bactericidal and direct anti-inflammatory properties International immunopharmacology 2023-09-14 [PMID: 37716162] (Human)
• Tran, TT;Phung, TTB;Tran, DM;Bui, HT;Nguyen, PTT;Vu, TT;Ngo, NTP;Nguyen, MT;Nguyen, AH;Nguyen, ATV; Efficient symptomatic treatment and viral load reduction for children with influenza virus infection by nasal-spraying Bacillus spore probiotics Scientific reports 2023-09-08 [PMID: 37684332] (Human)
• Burger, K;Jung, F;Baumann, A;Brandt, A;Staltner, R;Sánchez, V;Bergheim, I; TNF? is a key trigger of inflammation in diet-induced non-obese MASLD in mice Redox biology 2023-09-01 [PMID: 37683301] (Human)
• Cao, QT;Ishak, M;Shpilman, I;Hirota, JA; TNF-? and Poly(I:C) induction of A20 and activation of NF-?B signaling are independent of ABCF1 in human airway epithelial cells Scientific reports 2023-09-07 [PMID: 37679460] (Human)
• Twarog, M;Schustak, J;Xu, Y;Coble, M;Dolan, K;Esterberg, R;Huang, Q;Saint-Geniez, M;Bao, Y; TNF? induced by DNA-sensing in macrophage compromises retinal pigment epithelial (RPE) barrier function Scientific reports 2023-09-02 [PMID: 37660150] (Human)
• Montezano, AC;Camargo, LL;Mary, S;Neves, KB;Rios, FJ;Stein, R;Lopes, RA;Beattie, W;Thomson, J;Herder, V;Szemiel, AM;McFarlane, S;Palmarini, M;Touyz, RM; SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication Scientific reports 2023-08-28 [PMID: 37640791] (Human)
• Jeon, S;Jeon, JH;Jeong, J;Kim, G;Lee, S;Kim, S;Maruthupandy, M;Lee, K;Yang, SI;Cho, WS; Size- and oxidative potential-dependent toxicity of environmentally relevant expanded polystyrene styrofoam microplastics to macrophages Journal of hazardous materials 2023-08-14 [PMID: 37597397] (Human)
• Faria, J;Ahmed, S;Stamatialis, D;Verhaar, MC;Masereeuw, R;Gerritsen, KGF;Mih?il?, SM; Bioengineered Kidney Tubules Efficiently Clear Uremic Toxins in Experimental Dialysis Conditions International journal of molecular sciences 2023-08-04 [PMID: 37569805] (Human)
• Lindquist, S;Wang, Y;Andersson, EL;Tsuji Grebe, S;Alenius, GM;Rantapää-Dahlqvist, S;Lundberg, L;Hernell, O; Effects of bile salt-stimulated lipase on blood cells and associations with disease activity in human inflammatory joint disorders PloS one 2023-08-11 [PMID: 37566600] (Human)
• Grubczak, K;Starosz, A;Makowska, B;Parfienowicz, Z;Kr?towska, M;Naumnik, B;Moniuszko, M; The influence of calcitriol and methylprednisolone on podocytes function in minimal change disease in vitro model Scientific reports 2023-08-05 [PMID: 37543700] (Human)
• Zhou, L;Fang, L;Tamm, M;Stolz, D;Roth, M; Extracellular Heat Shock Protein 70 Increases the Glucocorticoid Receptor and Dual-Specificity Phosphatase 1 via Toll-like Receptor 4 and Attenuates Inflammation in Airway Epithelial Cells International journal of molecular sciences 2023-07-20 [PMID: 37511459] (Human)
• Letícia Martins SANTOS, Patricia e Silva CARDOSO, Elisa Abreu DINIZ, Juliana Garuba RAHHAL, Carla Renata SIPERT Different concentrations of fetal bovine serum affect cytokine modulation in Lipopolysaccharide-activated apical papilla cells in vitro* Journal of Applied Oral Science 2023-07-24 [PMID: 37493700] (Human)
• Matsunaga, T;Sano, H;Takita, K;Morita, M;Yamanaka, S;Ichikawa, T;Numakura, T;Ida, T;Jung, M;Ogata, S;Yoon, S;Fujino, N;Kyogoku, Y;Sasaki, Y;Koarai, A;Tamada, T;Toyama, A;Nakabayashi, T;Kageyama, L;Kyuwa, S;Inaba, K;Watanabe, S;Nagy, P;Sawa, T;Oshiumi, H;Ichinose, M;Yamada, M;Sugiura, H;Wei, FY;Motohashi, H;Akaike, T; Supersulphides provide airway protection in viral and chronic lung diseases Nature communications 2023-07-25 [PMID: 37491435] (Human)
• Malaga, W;Payros, D;Meunier, E;Frigui, W;Sayes, F;Pawlik, A;Orgeur, M;Berrone, C;Moreau, F;Mazères, S;Gonzalo-Asensio, J;Rengel, D;Martin, C;Astarie-Dequeker, C;Mourey, L;Brosch, R;Guilhot, C; Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli PLoS pathogens 2023-07-01 [PMID: 37450466] (Human)
• Isanejad, A;Nazari, S;Gharib, B;Motlagh, AG; Comparison of the effects of high-intensity interval and moderate-intensity continuous training on inflammatory markers, cardiorespiratory fitness, and quality of life in breast cancer patients Journal of sport and health science 2023-07-07 [PMID: 37423313] (Human)
• Kalsi, KK;Jackson, S;Baines, DL; Lipoxin receptor agonist and inhibition of LTA4 hydrolase prevent tight junction disruption caused by P. aeruginosa filtrate in airway epithelial cells PloS one 2023-07-05 [PMID: 37406028] ( Human)
• Vieira, SF;Araújo, J;Gonçalves, VMF;Fernandes, C;Pinto, M;Ferreira, H;Neves, NM;Tiritan, ME; Synthesis and Anti-Inflammatory Evaluation of a Library of Chiral Derivatives of Xanthones Conjugated with Proteinogenic Amino Acids International journal of molecular sciences 2023-06-19 [PMID: 37373503] (Human)
• Kirsten, N;Ohmes, J;Mikkelsen, MD;Nguyen, TT;Blümel, M;Wang, F;Tasdemir, D;Seekamp, A;Meyer, AS;Fuchs, S; Impact of Enzymatically Extracted High Molecular Weight Fucoidan on Lipopolysaccharide-Induced Endothelial Activation and Leukocyte Adhesion Marine drugs 2023-05-31 [PMID: 37367664] (Human)
• Ferreira, AV;Kostidis, S;Groh, LA;Koeken, VACM;Bruno, M;Baydemir, I;Kilic, G;Bulut, Ö;Andriopoulou, T;Spanou, V;Synodinou, KD;Gkavogianni, T;Moorlag, SJCFM;Charlotte de Bree, L;Mourits, VP;Matzaraki, V;Koopman, WJH;van de Veerdonk, FL;Renieris, G;Giera, M;Giamarellos-Bourboulis, EJ;Novakovic, B;Domínguez-Andrés, J; Dimethyl itaconate induces long-term innate immune responses and confers protection against infection Cell reports 2023-06-16 [PMID: 37330914] ( Human)
• Warren, KJ;Beck, EM;Callahan, SJ;Helms, MN;Middleton, E;Maddock, S;Carr, JR;Harris, D;Blagev, DP;Lanspa, MJ;Brown, SM;Paine, R; Alveolar macrophages from EVALI patients and e-cigarette users: a story of shifting phenotype Respiratory research 2023-06-17 [PMID: 37330506] (Human)
• Langgartner, D;Winkler, R;Brunner-Weisser, J;Rohleder, N;Jarczok, MN;Gündel, H;Weimer, K;Reber, SO; COVID-19 vaccination exacerbates ex vivo IL-6 release from isolated PBMCs Scientific reports 2023-06-12 [PMID: 37308487] (Human)
• Chang, JP;Chang, SS;Chen, HT;Chien, YC;Yang, HT;Huang, SY;Tseng, PT;Chang, CH;Galecki, P;Su, KP; Omega-3 polyunsaturated fatty acids (n-3 PUFAs), somatic and fatigue symptoms in cardiovascular diseases comorbid major depressive disorder (MDD): A randomized controlled trial Brain, behavior, and immunity 2023-06-09 [PMID: 37301235] (Human)
• Toffoli, B;Tonon, F;Giudici, F;Ferretti, T;Ghirigato, E;Contessa, M;Francica, M;Candido, R;Puato, M;Grillo, A;Fabris, B;Bernardi, S; Preliminary Study on the Effect of a Night Shift on Blood Pressure and Clock Gene Expression International journal of molecular sciences 2023-05-26 [PMID: 37298261] (Human)
• Gjörloff Wingren, A;Ziyad Faik, R;Holefors, A;Filecovic, E;Gustafsson, A; In vitro effects of undifferentiated callus extracts from Plantago major L, Rhodiola rosea L and Silybum marianum L in normal and malignant human skin cells Heliyon 2023-06-01 [PMID: 37292297] (Human)
• Meade, RD;Notley, SR;Akerman, AP;McCormick, JJ;King, KE;Sigal, RJ;Kenny, GP; Efficacy of Cooling Centers for Mitigating Physiological Strain in Older Adults during Daylong Heat Exposure: A Laboratory-Based Heat Wave Simulation Environmental health perspectives 2023-06-01 [PMID: 37262028] (Human)
• Li, C;Ture, SK;Nieves-Lopez, B;Blick-Nitko, SK;Maurya, P;Livada, AC;Stahl, TJ;Kim, M;Pietropaoli, AP;Morrell, CN; Thrombocytopenia Independently Leads to Monocyte Immune Dysfunction bioRxiv : the preprint server for biology 2023-05-12 [PMID: 37214993] (Human)
• Jeon, KB;Kim, J;Lim, CM;Park, JY;Kim, NY;Lee, J;Oh, DK;Yoon, DY; Unsaturated oxidated fatty acid 12(S)-HETE attenuates TNF-? expression in TNF-?/IFN-?-stimulated human keratinocytes International immunopharmacology 2023-05-17 [PMID: 37207444] (Human)
• Montero, P;Roger, I;Estornut, C;Milara, J;Cortijo, J; Influence of dose and exposition time in the effectiveness of N-Acetyl-l-cysteine treatment in A549 human epithelial cells Heliyon 2023-05-01 [PMID: 37144195] (Human)
• A Chovsepian, O Prokopchuk, G Petrova, T Gjini, H Kuzi, S Heisz, KP Janssen, ME Martignoni, H Friess, H Hauner, M Rohm Diabetes increases mortality in patients with pancreatic and colorectal cancer by promoting cachexia and its associated inflammatory status Molecular Metabolism, 2023-04-22;0(0):101729. 2023-04-22 [PMID: 37094629] (Human)
• P Banerjee, AR Mehta, RS Nirujogi, J Cooper, OG James, J Nanda, J Longden, K Burr, K McDade, A Salzinger, E Paza, J Newton, D Story, S Pal, C Smith, DR Alessi, BT Selvaraj, J Priller, S Chandran Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72-ALS iPSC-derived microglia contributes to neurodegeneration Science Advances, 2023-04-21;9(16):eabq0651. 2023-04-21 [PMID: 37083530] (Human)
• YH Chen, D Nguyen, S Brindley, T Ma, T Xia, J Brune, JM Brown, CS Tsai The dependence of particle size on cell toxicity for modern mining dust Scientific Reports, 2023-03-29;13(1):5101. 2023-03-29 [PMID: 36991007] (Human)
• Y Guo, V Kanamarlap Molecular Analysis of SARS-CoV-2 Spike Protein-Induced Endothelial Cell Permeability and vWF Secretion International Journal of Molecular Sciences, 2023-03-16;24(6):. 2023-03-16 [PMID: 36982738] (Human)
• S Speaks, A Zani, A Solstad, A Kenney, L Zhang, AC Eddy, AO Amer, R Robinson, C Cai, J Ma, EA Hemann, A Forero, JS Yount Loss of Gasdermin D is protective against influenza virus-induced inflammation and mortality bioRxiv : the preprint server for biology, 2023-04-07;0(0):. 2023-04-07 [PMID: 36945485] (Human)
• M Liu, AN Panagopoul, UM Oguz, S Samant, CH Vasa, DK Agrawal, YS Chatzizisi Role of triggering receptor expressed on myeloid cells-1 in the mechanotransduction signaling pathways that link low shear stress with inflammation Scientific Reports, 2023-03-21;13(1):4656. 2023-03-21 [PMID: 36944850] (Human)
• A Jurj, O Zanoaga, L Raduly, V Morhan, Z Papi, C Ciocan, LA Pop, I Berindan-N, C Braicu Discovering the Biological Significance and Therapeutic Potential of miR-29b-3p in Triple-Negative Breast Cancer International Journal of Molecular Sciences, 2023-03-06;24(5):. 2023-03-06 [PMID: 36902482] (Human)
• R Danielsson, N Ferey, I Mile, H Eriksson Metabolic Reprogramming of Macrophages upon In Vitro Incubation with Aluminum-Based Adjuvant International Journal of Molecular Sciences, 2023-02-23;24(5):. 2023-02-23 [PMID: 36901849] (Human)
• V Klück, G Cab?u, L Mies, F Bukkems, L van Emst, R Bakker, A van Caam, HINT conso, TO Cri?an, LAB Joosten TGF-beta is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cells Arthritis Research & Therapy, 2023-02-27;25(1):30. 2023-02-27 [PMID: 36850003] (Human)
• M Shafiq, ZR Lone, AO Abdulkaree, G Kaur, S Navya, H Singh, K Jagavelu, K Hanif Inhibition of poly (ADP-ribose) Polymerase-1 (PARP-1) improves endothelial function in pulmonary hypertension Pulmonary pharmacology & therapeutics, 2023-02-25;0(0):102200. 2023-02-25 [PMID: 36842770] (Human)
• R Nicu, DE Ciolacu, AR Petrovici, D Rusu, M Avadanei, AC Mihaila, E Butoi, F Ciolacu 3D Matrices for Enhanced Encapsulation and Controlled Release of Anti-Inflammatory Bioactive Compounds in Wound Healing International Journal of Molecular Sciences, 2023-02-20;24(4):. 2023-02-20 [PMID: 36835619] (Human)
• KB Neves, R Alves-Lope, AC Montezano, RM Touyz Role of PARP and TRPM2 in VEGF Inhibitor-Induced Vascular Dysfunction Journal of the American Heart Association, 2023-02-20;0(0):e027769. 2023-02-20 [PMID: 36802924] (Human)
• AJ Heires, D Samuelson, D Villageliu, TM Nordgren, DJ Romberger Agricultural dust derived bacterial extracellular vesicle mediated inflammation is attenuated by DHA Scientific Reports, 2023-02-16;13(1):2767. 2023-02-16 [PMID: 36797300] (Human)
• LU Teufel, MG Netea, FL van de Vee, CA Dinarello, LAB Joosten, RJW Arts Opposing Effects of Interleukin-36gamma and Interleukin-38 on Trained Immunity International Journal of Molecular Sciences, 2023-01-24;24(3):. 2023-01-24 [PMID: 36768634] (Human)
• RL Schmitz, KE Tweed, P Rehani, K Samimi, J Riendeau, I Jones, EM Maly, EC Guzman, MH Forsberg, A Shahi, CM Capitini, AJ Walsh, MC Skala Autofluorescence lifetime imaging classifies human lymphocyte activation and subtype bioRxiv : the preprint server for biology, 2023-01-23;0(0):. 2023-01-23 [PMID: 36747690] (Human)
• M Nicolas, M Lasalo, S Chow, C Antheaume, K Huet, E Hnawia, GJ Guillemin, M Nour, M Matsui Anti-inflammatory activities of Coleus forsteri (formerly Plectranthus forsteri) extracts on human macrophages and chemical characterization Frontiers in Pharmacology, 2023-01-09;13(0):1081310. 2023-01-09 [PMID: 36699063] (Human)
• G Bredeck, M Busch, A Rossi, B Stahlmecke, KW Fomba, H Herrmann, RPF Schins Inhalable Saharan dust induces oxidative stress, NLRP3 inflammasome activation, and inflammatory cytokine release Environment international, 2023-01-11;172(0):107732. 2023-01-11 [PMID: 36680803] (Human)
• A Dinarello, TS Mills, IW Tengesdal, NE Powers, T Azam, CA Dinarello Dexamethasone and OLT1177 Cooperate in the Reduction of Melanoma Growth by Inhibiting STAT3 Functions Cells, 2023-01-12;12(2):. 2023-01-12 [PMID: 36672229] (Human)
• M Liu, S Samant, CH Vasa, RM Pedrigi, UM Oguz, S Ryu, T Wei, DR Anderson, DK Agrawal, YS Chatzizisi Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis PLoS ONE, 2023-01-20;18(1):e0280385. 2023-01-20 [PMID: 36662769] (Human)
• TTT Nguyen, YH Choi, WK Lee, Y Ji, E Chun, YH Kim, JE Lee, HS Jung, JH Suh, S Kim, M Jin Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses Cell Reports, 2022-12-30;42(1):111905. 2022-12-30 [PMID: 36640342] (Human)
• N Lagneau, P Tournier, B Halgand, F Loll, Y Maugars, J Guicheux, C Le Visage, V Delplace Click and bioorthogonal hyaluronic acid hydrogels as an ultra-tunable platform for the investigation of cell-material interactions Bioactive materials, 2023-01-03;24(0):438-449. 2023-01-03 [PMID: 36632500] (Human)
• J Siewiera, K Brodaczews, N Jermakow, A Lubas, K K?os, A Majewska, J Kot Effectiveness of Hyperbaric Oxygen Therapy in SARS-CoV-2 Pneumonia: The Primary Results of a Randomised Clinical Trial Journal of Clinical Medicine, 2022-12-20;12(1):. 2022-12-20 [PMID: 36614808] (Human)
• K Shabir, S Gharanei, S Orton, V Patel, P Chauhan, E Karteris, HS Randeva, JE Brown, I Kyrou Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway International Journal of Molecular Sciences, 2022-12-23;24(1):. 2022-12-23 [PMID: 36613673] (Human)
• K Wadowska, P B?asiak, A Rzechonek, I Bil-Lula, M ?liwi?ska- Hepcidin as a Diagnostic Biomarker in Anaemic Lung Cancer Patients Cancers, 2022-12-30;15(1):. 2022-12-30 [PMID: 36612220] (Human)
• Q Huang, M Peng, Y Gu, J Wu, Y Zhan, Z Deng, S Chen, R Yang, J Chen, J Xie Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium Oxidative Medicine and Cellular Longevity, 2022-12-19;2022(0):7067623. 2022-12-19 [PMID: 36578523] (Human)
• GA Bonaterra, J Schmitt, K Schneider, H Schwarzbac, H Aziz-Kalbh, O Kelber, J Müller, R Kinscherf Phytohustil� and root extract of Althaea officinalis L. exert anti-inflammatory and anti-oxidative properties and improve the migratory capacity of endothelial cells in vitro Frontiers in Pharmacology, 2022-12-08;13(0):948248. 2022-12-08 [PMID: 36569306] (Human)
• AO Larsson, M Hultström, R Frithiof, M Lipcsey, MB Eriksson Shrunken Pore Syndrome Is Frequently Occurring in Severe COVID-19 International Journal of Molecular Sciences, 2022-12-10;23(24):. 2022-12-10 [PMID: 36555328] (Human)
• Y Hosokawa, I Hosokawa, M Shimoyama, A Fujii, J Sato, K Kadena, K Ozaki, K Hosaka The Anti-Inflammatory Effects of Iberin on TNF-alpha-Stimulated Human Oral Epithelial Cells: In Vitro Research Biomedicines, 2022-12-06;10(12):. 2022-12-06 [PMID: 36551911] (Human)
• F Cognasse, H Hamzeh-Cog, M Rosa, D Corseaux, B Bonneaudea, C Pierre, J Huet, CA Arthaud, MA Eyraud, A Prier, AC Duchez, T Ebermeyer, M Heesterman, E Audoux-Cai, Q Philippot, T Le Voyer, O Hequet, AM Fillet, P Chavarin, D Legrand, P Richard, F Pirenne, P Gallian, JL Casanova, S Susen, P Morel, K Lacombe, P Bastard, P Tiberghien Inflammatory markers and auto-Abs to type I IFNs in COVID-19 convalescent plasma cohort study EBioMedicine, 2022-12-17;87(0):104414. 2022-12-17 [PMID: 36535107] (Human)
• LAC Teixeira, JM Dos Santos, AN Parentoni, LP Lima, TC Duarte, FP Brant, CDC Neves, FSM Pereira, NCP Avelar, AL Danielewic, AAO Leopoldino, SP Costa, AN Arrieiro, LA Soares, ACN Prates, JNP Nobre, A de Carvalh, VC de Oliveir, MX Oliveira, PH Scheidt Fi, HS Costa, V Amaral Men, R Taiar, AC Rodrigues Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study Journal of Clinical Medicine, 2022-12-02;11(23):. 2022-12-02 [PMID: 36498747] (Human)
• M Fassler, C Benaim, J George A Single Chain Fragment Variant Binding Misfolded Alpha-Synuclein Exhibits Neuroprotective and Antigen-Specific Anti-Inflammatory Properties Cells, 2022-11-29;11(23):. 2022-11-29 [PMID: 36497081] (Human)
• LU Teufel, CI van der Ma, V Klück, A Simons, A Hoischen, V Vernimmen, LAB Joosten, RJW Arts Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study Cytokine, 2022-12-05;162(0):156102. 2022-12-05 [PMID: 36476991] (Human)
• T Luong, E Cukierman Eribulin normalizes pancreatic cancer-associated fibroblasts by simulating selected features of TGFbeta inhibition BMC Cancer, 2022-12-02;22(1):1255. 2022-12-02 [PMID: 36461015] (Human)
• VC Capetini, BJ Quintanilh, DC de Oliveir, AH Nishioka, LA de Matos, LRP Ferreira, FM Ferreira, GR Sampaio, NMA Hassimotto, FM Lajolo, RA Fock, MM Rogero Blood orange juice intake modulates plasma and PBMC microRNA expression in overweight and insulin resistance women: impact on MAPK and NFkappaB signaling pathways The Journal of nutritional biochemistry, 2022-11-26;0(0):109240. 2022-11-26 [PMID: 36442716] (Human)
• JS Park, SC Yang, HY Jeong, SY Lee, JG Ryu, JW Choi, HY Kang, SM Kim, SH Hwang, ML Cho, SH Park EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis Arthritis Research & Therapy, 2022-11-17;24(1):254. 2022-11-17 [PMID: 36397156] (Human)
• MJ Barnes, D Lomiwes, DAD Parry, S Mackintosh An experimental model of contusion injury in humans PLoS ONE, 2022-11-17;17(11):e0277765. 2022-11-17 [PMID: 36395119] (Human)
• CS Rigazio, N Mariz-Pont, EP Caballero, FN Penas, NB Goren, MH Santamaría, RS Corral Involvement of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor in proinflammatory mechanisms promoting cardiovascular injury mechanisms promoting cardiovascular inflammation tThe combined action of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor increases proinflammatory mediator production by cardiomyocytes and vascular endothelial cells Microbial pathogenesis, 2022-11-12;0(0):105881. 2022-11-12 [PMID: 36379373] (Human)
• SF Vieira, VMF Gonçalves, CP Llaguno, F Macías, ME Tiritan, RL Reis, H Ferreira, NM Neves On the Bioactivity of Echinacea purpurea Extracts to Modulate the Production of Inflammatory Mediators Oncogene, 2022-11-06;23(21):. 2022-11-06 [PMID: 36362404] (Human)
• B Saravi, Z Li, V Basoli, S Grad, S Häckel, CE Albers, M Alini, H Schmal, P Obid, G Lang In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells Cells, 2022-10-28;11(21):. 2022-10-28 [PMID: 36359814] (Human)
• J Park, D Kim, M Lee, S Han, W Jun, HM Jung, YK Koo, GH Na, SH Han, J Han, OK Kim Enzyme-Treated Caviar Prevents UVB Irradiation-Induced Skin Photoaging Oncogene, 2022-10-30;20(11):. 2022-10-30 [PMID: 36355008] (Human)
• L Butcher, JC Zaldua, JA Carnicero, K Hawkins, J Whitley, R Mothukuri, PA Evans, K Morris, S Pillai, JD Erusalimsk High levels of soluble RAGE are associated with a greater risk of mortality in COVID-19 patients treated with dexamethasone Respiratory Research, 2022-11-05;23(1):303. 2022-11-05 [PMID: 36335329] (Human)
• G Mariananto, G Meogrossi, E Tollapi, A Rencinai, J Brunetti, C Marruganti, C Gaeta, A Pini, L Bracci, M Ferrari, S Grandini, C Falciani Antimicrobial Peptides Active in In Vitro Models of Endodontic Bacterial Infections Modulate Inflammation in Human Cardiac Fibroblasts Pharmaceutics, 2022-09-29;14(10):. 2022-09-29 [PMID: 36297519] (Human)
• W Dieterich, C Schuster, P Gundel, KA Scherf, D Pronin, S Geisslitz, A Börner, MF Neurath, Y Zopf Proteins from Modern and Ancient Wheat Cultivars: Impact on Immune Cells of Healthy Individuals and Patients with NCGS Nutrients, 2022-10-12;14(20):. 2022-10-12 [PMID: 36296938] (Human)
• H Wang, Y Li, Z Yue, Y Liu, Q Chen, D Hu, J Han Adipose-Derived Stem Cell Exosomes Inhibit Hypertrophic Scaring Formation by Regulating Th17/Treg Cell Balance BioMed Research International, 2022-10-12;2022(0):9899135. 2022-10-12 [PMID: 36277890] (Human)
• M Patankar, M Li, A Khalatbari, JD Castle, L Hu, C Zhang, A Shaker Inflammatory and Proliferative Pathway Activation in Human Esophageal Myofibroblasts Treated with Acidic Bile Salts International Journal of Molecular Sciences, 2022-09-08;23(18):. 2022-09-08 [PMID: 36142285] (Human)
• R Lei, H Arain, M Obaid, N Sabhnani, C Mohan Ultra-Sensitive and Semi-Quantitative Vertical Flow Assay for the Rapid Detection of Interleukin-6 in Inflammatory Diseases Biosensors, 2022-09-14;12(9):. 2022-09-14 [PMID: 36140141] (Human)
• V Dani, S Bruni-Favi, B Chignon-Si, A Loubat, A Doglio, C Dani Regulation of Adipose Progenitor Cell Expansion in a Novel Micro-Physiological Model of Human Adipose Tissue Mimicking Fibrotic and Pro-Inflammatory Microenvironments Cells, 2022-09-07;11(18):. 2022-09-07 [PMID: 36139371] (Human)
• P Marona, J Górka, O Kwapisz, J Jura, J Rys, RM Hoffman, K Miekus Resistance to tyrosine kinase inhibitors promotes renal cancer progression through MCPIP1 tumor-suppressor downregulation and c-Met activation Cell Death & Disease, 2022-09-22;13(9):814. 2022-09-22 [PMID: 36138026] (Human, Mouse)
• Kartasheva-Ebertz D, Gaston J, Lair-Mehiri L, Mottez E, Buivan T, Massault P, Scatton O, Gaujoux S, Vaillant J, Pol S, Lagaye S IL-17A in Human Liver: Significant Source of Inflammation and Trigger of Liver Fibrosis Initiation. Int J Mol Sci, 2022-08-29;23(17):. 2022-08-29 [PMID: 36077175] (Human)
• E The, DM de Graaf, Y Zhai, Q Yao, L Ao, DA Fullerton, CA Dinarello, X Meng Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3 Proceedings of the National Academy of Sciences of the United States of America, 2022-08-29;119(36):e2202577119. 2022-08-29 [PMID: 36037361] (Human)
• M Shafiq, ZR Lone, P Bharati, S Mahapatra, P Rai, N Khandelwal, AN Gaikwad, K Jagavelu, K Hanif Pyrroloquinoline quinone (PQQ) improves pulmonary hypertension by regulating mitochondrial and metabolic functions Pulmonary pharmacology & therapeutics, 2022-08-25;76(0):102156. 2022-08-25 [PMID: 36030026] (Rat)
• L Bolkun, M Tynecka, T Wasiluk, J Piszcz, A Starosz, K Grubczak, M Moniuszko, A Eljaszewic A Proliferation-Inducing Ligand and B-Cell Activating Factor Are Upregulated in Patients with Essential Thrombocythemia Journal of Clinical Medicine, 2022-08-09;11(16):. 2022-08-09 [PMID: 36012902] (Human)
• L Sansone, A de Iure, M Cristina, M Belli, L Vitiello, F Marcolongo, A Rosellini, L Macera, PG Spezia, C Tomino, S Bonassi, MA Russo, F Maggi, P Russo Nicotine in Combination with SARS-CoV-2 Affects Cells Viability, Inflammatory Response and Ultrastructural Integrity International Journal of Molecular Sciences, 2022-08-22;23(16):. 2022-08-22 [PMID: 36012747] (Human)
• C Amormino, V Tedeschi, G Paldino, S Arcieri, MT Fiorillo, A Paiardini, L Tuosto, M Kunkl SARS-CoV-2 Spike Does Not Possess Intrinsic Superantigen-like Inflammatory Activity Cells, 2022-08-15;11(16):. 2022-08-15 [PMID: 36010602] (Human)
• S Manandhar, A Scott-Thom, M Harrington, P Sinha, A Pilbrow, AM Richards, V Cameron, M Bhatia, ST Chambers Hydrogen Sulfide and Substance P Levels in Patients with Escherichia coli and Klebsiella pneumoniae Bacteraemia International Journal of Molecular Sciences, 2022-08-03;23(15):. 2022-08-03 [PMID: 35955767] (Human)
• JK Pfromm, M Bonillo, D Dauletbeko, K Bucher, MD Fischer Plasmid-mediated gene transfer of Cas9 induces vector-related but not SpCas9-related immune responses in human retinal pigment epithelial cells Scientific Reports, 2022-08-01;12(1):13202. 2022-08-01 [PMID: 35915300] (Human)
• Y Xu, M Twarog, N Li, A Banks, J Schustak, Y Bao, Q Huang, QG Medley Zinc transport from the endoplasmic reticulum to the cytoplasm via Zip7 is necessary for barrier dysfunction mediated by inflammatory signaling in RPE cells PLoS ONE, 2022-07-28;17(7):e0271656. 2022-07-28 [PMID: 35901031] (Human)
• OA Chaves, N Fintelman-, X Wang, CQ Sacramento, JR Temerozo, AC Ferreira, M Mattos, F Pereira-Du, PT Bozza, HC Castro-Far, JJ Russo, J Ju, TML Souza Commercially Available Flavonols Are Better SARS-CoV-2 Inhibitors than Isoflavone and Flavones Viruses, 2022-06-30;14(7):. 2022-06-30 [PMID: 35891437] (Human)
• M Anselmi, F Fontana, M Marzagalli, N Gagliano, M Sommariva, P Limonta Melanoma Stem Cells Educate Neutrophils to Support Cancer Progression Cancers, 2022-07-13;14(14):. 2022-07-13 [PMID: 35884452] (Human)
• S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis Journal of ovarian research, 2022-07-26;15(1):87. 2022-07-26 [PMID: 35883110] (Human)
• J Hu, Y Zhang, S Yi, C Wang, X Huang, S Pan, J Yang, G Yuan, S Tan, H Li Lithocholic acid inhibits dendritic cell activation by reducing intracellular glutathione via TGR5 signaling International journal of biological sciences, 2022-07-11;18(11):4545-4559. 2022-07-11 [PMID: 35864954] (Human)
• LAJ Feather, V Nadella, E Kastner, Y Perrie, AC Hilton, A Devitt Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems Scientific Reports, 2022-07-20;12(1):12448. 2022-07-20 [PMID: 35859154] (Human)
• DM Tran, TT Tran, TTB Phung, HT Bui, PTT Nguyen, TT Vu, NTP Ngo, MT Nguyen, AH Nguyen, ATV Nguyen Nasal-spraying Bacillus spores as an effective symptomatic treatment for children with acute respiratory syncytial virus infection Scientific Reports, 2022-07-20;12(1):12402. 2022-07-20 [PMID: 35858943] (Human)
• H Stölting, L Baillon, R Frise, K Bonner, RJ Hewitt, PL Molyneaux, ML Gore, Breathing, WS Barclay, S Saglani, CM Lloyd Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1 Mucosal Immunology, 2022-07-15;0(0):. 2022-07-15 [PMID: 35840680] (Human)
• RA Wagdy, PJ Chen, MM Hamed, SS Darwish, SH Chen, AH Abadi, M Abdel-Hali, TL Hwang, M Engel From EGFR kinase inhibitors to anti-inflammatory drugs: Optimization and biological evaluation of (4-(phenylamino)quinazolinyl)-phenylthiourea derivatives as novel NF-kappaB inhibitors Bioorganic chemistry, 2022-06-18;127(0):105977. 2022-06-18 [PMID: 35779404] (Human)
• S Zhao, Z Huang, H Jiang, J Xiu, L Zhang, Q Long, Y Yang, L Yu, L Lu, H Gu Sirtuin 1 Induces Choroidal Neovascularization and Triggers Age-Related Macular Degeneration by Promoting LCN2 through SOX9 Deacetylation Oncogene, 2022-06-09;2022(0):1671438. 2022-06-09 [PMID: 35720180] (Human)
• MHA Bakar, NSN Shahril, MSFM Khalid, S Mohammad, KA Shariff, T Karunakara, RM Salleh, MN Rosdi Celastrol alleviates high-fat diet-induced obesity via enhanced muscle glucose utilization and mitochondrial oxidative metabolism-mediated upregulation of pyruvate dehydrogenase complex Oncogene, 2022-06-06;449(0):116099. 2022-06-06 [PMID: 35679966] (Mouse)
• JT de Kay, J Carver, B Shevenell, AM Kosta, S Tsibulniko, E Certo, DB Sawyer, S Ryzhov, MP Robich Decreased expression of ErbB2 on left ventricular epicardial cells in patients with diabetes mellitus Cellular Signalling, 2022-05-21;96(0):110360. 2022-05-21 [PMID: 35609807] (Human)
• V Artusa, C Ciaramelli, A D'Aloia, FA Facchini, N Gotri, A Bruno, B Costa, A Palmioli, C Airoldi, F Peri Green and Roasted Coffee Extracts Inhibit Interferon-beta Release in LPS-Stimulated Human Macrophages Frontiers in Pharmacology, 2022-05-05;13(0):806010. 2022-05-05 [PMID: 35600887] (Human)
• L Homann, M Rentschler, E Brenner, K Böhm, M Röcken, T Wieder IFN-gamma and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma Cells, 2022-04-30;11(9):. 2022-04-30 [PMID: 35563820] (Human)
• Y Zhan, J Chen, J Wu, Y Gu, Q Huang, Z Deng, S Chen, X Wu, Y Lv, Z Zeng, J Xie Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease Respiratory Research, 2022-05-12;23(1):120. 2022-05-12 [PMID: 35550579] (Human)
• KN Lee, KH Park, YM Kim, I Cho, TE Kim Prediction of emergency cerclage outcomes in women with cervical insufficiency: The role of inflammatory, angiogenic, and extracellular matrix-related proteins in amniotic fluid PLoS ONE, 2022-05-10;17(5):e0268291. 2022-05-10 [PMID: 35536791] (Human)
• MJ Yu, C Li, SS Deng, XM Meng, RS Yao Discovery of a novel GRPR antagonist for protection against cisplatin-induced acute kidney injury Bioorganic chemistry, 2022-04-06;124(0):105794. 2022-04-06 [PMID: 35533545] (Human)
• S Novello, S Tricot-Dol, A Novella, P Pellen-Mus, S Jeanne Influence of Periodontal Ligament Stem Cell-Derived Conditioned Medium on Osteoblasts Pharmaceutics, 2022-03-28;14(4):. 2022-03-28 [PMID: 35456563] (Human)
• M Lipcsey, M Bergquist, R Sirén, A Larsson, F Huss, J Pravda, M Furebring, J Sjölin, H Janols Urine Hydrogen Peroxide Levels and Their Relation to Outcome in Patients with Sepsis, Septic Shock, and Major Burn Injury Biomedicines, 2022-04-05;10(4):. 2022-04-05 [PMID: 35453598] (Human)
• JR McCall, KT Sausman, DM Keeler, AP Brown, SL Turrise Immune Modulating Brevetoxins: Monocyte Cytotoxicity, Apoptosis, and Activation of M1/M2 Response Elements Is Dependent on Reactive Groups Marine Drugs, 2022-03-29;20(4):. 2022-03-29 [PMID: 35447906] (Human)
• M Dolci, L Signorini, S D'Alessand, F Perego, S Parapini, M Sommariva, D Taramelli, P Ferrante, N Basilico, S Delbue In Vitro SARS-CoV-2 Infection of Microvascular Endothelial Cells: Effect on Pro-Inflammatory Cytokine and Chemokine Release International Journal of Molecular Sciences, 2022-04-06;23(7):. 2022-04-06 [PMID: 35409421] (Human)
• P Esteves, B Allard, A Celle, I Dupin, E Maurat, O Ousova, M Thumerel, JW Dupuy, T Leste-Lass, R Marthan, PO Girodet, T Trian, P Berger Asthmatic bronchial smooth muscle increases rhinovirus replication within the bronchial epithelium Cell Reports, 2022-03-29;38(13):110571. 2022-03-29 [PMID: 35354045] (Human)
• J Ohmes, MD Mikkelsen, TT Nguyen, VHN Tran, S Meier, MS Nielsen, M Ding, A Seekamp, AS Meyer, S Fuchs Depolymerization of fucoidan with endo-fucoidanase changes bioactivity in processes relevant for bone regeneration Carbohydrate polymers, 2022-02-24;286(0):119286. 2022-02-24 [PMID: 35337530] (Human)
• LM de-Oliveir, VE Fiestas So, M de Lourdes, C Fernandes-, PH Damasco, MAMT de Siqueir, HG Dias, A Pauvolid-C, PV Damasco, EL de Azeredo Comparative Analysis of Circulating Levels of SARS-CoV-2 Antibodies and Inflammatory Mediators in Healthcare Workers and COVID-19 Patients Viruses, 2022-02-23;14(3):. 2022-02-23 [PMID: 35336861] (Human)
• E Singh, RAM Osmani, R Banerjee, AS Abu Lila, A Moin, K Almansour, HH Arab, HF Alotaibi, ES Khafagy Poly epsilon-Caprolactone Nanoparticles for Sustained Intra-Articular Immune Modulation in Adjuvant-Induced Arthritis Rodent Model Pharmaceutics, 2022-02-26;14(3):. 2022-02-26 [PMID: 35335895] (Human)
• H Farah, SN Wijesinghe, T Nicholson, F Alnajjar, M Certo, A Alghamdi, ET Davis, SP Young, C Mauro, SW Jones Differential Metabotypes in Synovial Fibroblasts and Synovial Fluid in Hip Osteoarthritis Patients Support Inflammatory Responses International Journal of Molecular Sciences, 2022-03-17;23(6):. 2022-03-17 [PMID: 35328687] (Human)
• A Divoux, E Erdos, K Whytock, TF Osborne, SR Smith Transcriptional and DNA Methylation Signatures of Subcutaneous Adipose Tissue and Adipose-Derived Stem Cells in PCOS Women Cells, 2022-03-01;11(5):. 2022-03-01 [PMID: 35269469] (Human)
• AR Cátala-Val, J Almeda, JN Bernard, AM Cole, AL Cole, SD Moore, CD Andl E-Cigarette Aerosols Promote Oral S. aureus Colonization by Delaying an Immune Response and Bacterial Clearing Cells, 2022-02-23;11(5):. 2022-02-23 [PMID: 35269394] (Human)
• G Szylar, R Wysoczansk, H Marshall, DJB Marks, R José, ME Ehrenstein, JS Brown A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site Scientific Reports, 2022-03-07;12(1):3990. 2022-03-07 [PMID: 35256717] (Human)
• S Eslick, EJ Williams, BS Berthon, T Wright, C Karihaloo, M Gately, LG Wood Weight Loss and Short-Chain Fatty Acids Reduce Systemic Inflammation in Monocytes and Adipose Tissue Macrophages from Obese Subjects Nutrients, 2022-02-11;14(4):. 2022-02-11 [PMID: 35215414] (Human)
• M O?dakowska, M ?ciskalska, M Kepinska, G Marek, H Milnerowic Association of Genetic Variants in IL6 Gene (rs1800795) with the Concentration of Inflammatory Markers (IL-6, hs-CRP) and Superoxide Dismutase in the Blood of Patients with Acute Pancreatitis-Preliminary Findings Genes, 2022-02-01;13(2):. 2022-02-01 [PMID: 35205334] (Human)
• R Gupta, P Gupta, Z Wang, A Seth, J Morrissey, I George, S Gandra, G Storch, B Parikh, G Genin, S Singamanen Plasmon-enhanced Quantitative Lateral Flow Assay for Femtomolar Detection of SARS-CoV-2 Antibodies and Antigens Research square, 2022-02-21;0(0):. 2022-02-21 [PMID: 35194598] (Human)
• J Zinngrebe, B Moepps, T Monecke, P Gierschik, F Schlichtig, TFE Barth, G Strau beta , E Boldrin, C Posovszky, A Schulz, O Beringer, E Rieser, EM Jacobsen, MR Lorenz, K Schwarz, U Pannicke, H Walczak, D Niessing, C Schuetz, P Fischer-Po, KM Debatin Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS Embo Molecular Medicine, 2022-02-16;0(0):e14901. 2022-02-16 [PMID: 35170849] (Human)
• B van der Lu, MCP Vos, M Grootte Br, N Ijssennagg, F Vrieling, J Meijerink, WT Steegenga The effects of sulfated secondary bile acids on intestinal barrier function and immune response in an inflammatory in vitro human intestinal model Heliyon, 2022-02-02;8(2):e08883. 2022-02-02 [PMID: 35169646] (Human)
• C Sun, M Janjic Ran, M Folwaczny, T Stocker, S Otto, A Wichelhaus, U Baumert Effect of Different Parameters of In Vitro Static Tensile Strain on Human Periodontal Ligament Cells Simulating the Tension Side of Orthodontic Tooth Movement International Journal of Molecular Sciences, 2022-01-28;23(3):. 2022-01-28 [PMID: 35163446] (Human)
• L Leppik, A Gempp, Z Kuçi, S Kuçi, P Bader, H Bönig, I Marzi, D Henrich A New Perspective for Bone Tissue Engineering: Human Mesenchymal Stromal Cells Well-Survive Cryopreservation on beta-TCP Scaffold and Show Increased Ability for Osteogenic Differentiation International Journal of Molecular Sciences, 2022-01-26;23(3):. 2022-01-26 [PMID: 35163348] (Human)
• YK Lin, CT Yeh, KT Kuo, IH Fong, VK Yadav, NG Kounis, P Hu, MY Hung Apolipoprotein (a)/Lipoprotein(a)-Induced Oxidative-Inflammatory alpha7-nAChR/p38 MAPK/IL-6/RhoA-GTP Signaling Axis and M1 Macrophage Polarization Modulate Inflammation-Associated Development of Coronary Artery Spasm Oxidative Medicine and Cellular Longevity, 2022-01-19;2022(0):9964689. 2022-01-19 [PMID: 35096275] (Human)
• R Pohl, S Feder, EM Haberl, L Rein-Fisch, TS Weiss, M Spirk, A Bruckmann, N McMullen, CJ Sinal, C Buechler Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis Biomedicines, 2022-01-07;10(1):. 2022-01-07 [PMID: 35052810] (Human)
• Y Gu, J Chen, Q Huang, Y Zhan, T Wang, J Wu, J Zhao, Z Zeng, Y Lv, C Xiao, J Xie MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema Oxidative Medicine and Cellular Longevity, 2022-01-07;2022(0):9300269. 2022-01-07 [PMID: 35035670] (Human)
• P Brandi, L Conejero, FJ Cueto, S Martínez-C, G Dunphy, MJ Gómez, C Relaño, P Saz-Leal, M Enamorado, A Quintas, A Dopazo, J Amores-Ini, C Del Fresno, E Nistal-Vil, C Ardavín, A Nieto, M Casanovas, JL Subiza, D Sancho Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections Cell Reports, 2022-01-04;38(1):110184. 2022-01-04 [PMID: 34986349] (Human)
• J Holl, C Pawlukiani, J Corton Rui, D Groth, K Grubczak, HR Hady, J Dadan, J Reszec, S Czaban, C Kowalewski, M Moniuszko, A Eljaszewic Skin Substitute Preparation Method Induces Immunomodulatory Changes in Co-Incubated Cells through Collagen Modification Pharmaceutics, 2021-12-15;13(12):. 2021-12-15 [PMID: 34959443] (Human)
• J Jhun, HS Na, KH Cho, J Kim, YM Moon, SY Lee, JS Lee, AR Lee, SJ Kim, ML Cho, SH Park A green-lipped mussel reduces pain behavior and chondrocyte inflammation and attenuated experimental osteoarthritis progression PLoS ONE, 2021-12-02;16(12):e0259130. 2021-12-02 [PMID: 34855756] (Human)
• C Valsecchi, S Croce, A Maltese, L Montagna, E Lenta, A Nevone, M Girelli, P Milani, T Bosoni, M Massa, C Abbà, R Campanelli, J Ripepi, A De Silvest, A Carolei, G Palladini, M Zecca, M Nuvolone, MA Avanzini Bone Marrow Microenvironment in Light-Chain Amyloidosis: In Vitro Expansion and Characterization of Mesenchymal Stromal Cells Biomedicines, 2021-10-22;9(11):. 2021-10-22 [PMID: 34829752] (Human)
• JW Kennedy, PM Tsimbouri, P Campsie, S Sood, PG Childs, S Reid, PS Young, DRM Meek, CS Goodyear, MJ Dalby Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures Scientific Reports, 2021-11-23;11(1):22741. 2021-11-23 [PMID: 34815449] (Human)
• JE Lee, KH Park, HJ Kim, YM Kim, JW Choi, S Shin, KN Lee Proteomic identification of novel plasma biomarkers associated with spontaneous preterm birth in women with preterm labor without infection/inflammation PLoS ONE, 2021-10-28;16(10):e0259265. 2021-10-28 [PMID: 34710180] (Human)
• N Mazarakis, RA Higgins, J Anderson, ZQ Toh, RB Luwor, KJ Snibson, TC Karagianni, LAH Do, PV Licciardi The effects of the dietary compound L-sulforaphane against respiratory pathogens International journal of antimicrobial agents, 2021-10-22;0(0):106460. 2021-10-22 [PMID: 34695564] (Human)
• M Griffiths, J Yang, D Vaidya, M Nies, S Brandal, DD Ivy, F Hickey, K Wolter-War, ED Austin, M Mullen, MW Pauciulo, KA Lutz, EB Rosenzweig, R Hirsch, D Yung, WC Nichols, AD Everett Biomarkers of Pulmonary Hypertension Are Altered in Children With Down Syndrome and Pulmonary Hypertension The Journal of pediatrics, 2021-10-21;0(0):. 2021-10-21 [PMID: 34687693] (Human)
• M Lale Ataei, M Karimipour, P Shahabi, R Pashaei-As, E Ebrahimie, M Pashaiasl The Restorative Effect of Human Amniotic Fluid Stem Cells on Spinal Cord Injury Cells, 2021-09-28;10(10):. 2021-09-28 [PMID: 34685545] (Rat)
• CA Minanni, A Machado-Li, RT Iborra, LS Okuda, R de Souza P, MFM Santana, ALA Lira, ER Nakandakar, MLC Côrrea-Gia, M Passarelli Persistent Effect of Advanced Glycated Albumin Driving Inflammation and Disturbances in Cholesterol Efflux in Macrophages Nutrients, 2021-10-17;13(10):. 2021-10-17 [PMID: 34684632] (Human)
• SR Bruno, A Kumar, ZF Mark, R Chandrasek, E Nakada, N Chamberlai, B Mihavics, J Walzer, J Cahoon, AE Dixon, B Cunniff, V Anathy DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen International Journal of Molecular Sciences, 2021-10-15;22(20):. 2021-10-15 [PMID: 34681784] (Human)
• N Yao, T Tretter, P Kvacskay, W Merkt, N Blank, HM Lorenz, LO Tykocinski Targeting of Janus Kinases Limits Pro-Inflammatory but Also Immunosuppressive Circuits in the Crosstalk between Synovial Fibroblasts and Lymphocytes Biomedicines, 2021-10-08;9(10):. 2021-10-08 [PMID: 34680530] (Human)
• SC Lean, RL Jones, SA Roberts, AEP Heazell A prospective cohort study providing insights for markers of adverse pregnancy outcome in older mothers BMC pregnancy and childbirth, 2021-10-20;21(1):706. 2021-10-20 [PMID: 34670515] (Human)
• N Kim, S Lee, J Kang, TK Kwon, D Khang, SH Kim Gomisin M2 alleviates psoriasis?like skin inflammation by inhibiting inflammatory signaling pathways Molecular Medicine Reports, 2021-10-19;24(6):. 2021-10-19 [PMID: 34664681] (Human)
• B Texler, A Zollner, V Reinstadle, SJ Reider, S Macheiner, B Jelusic, A Pfister, C Watschinge, N Przysiecki, H Tilg, H Oberacher, AR Moschen Tofacitinib-Induced Modulation of Intestinal Adaptive and Innate Immunity and Factors Driving Cellular and Systemic Pharmacokinetics Cellular and Molecular Gastroenterology and Hepatology, 2021-10-06;0(0):. 2021-10-06 [PMID: 34624526] (Human)
• N Niu, J Yao, RC Bast, AK Sood, J Liu IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming Oncogenesis, 2021-09-29;10(9):65. 2021-09-29 [PMID: 34588424] (Human)
• VE Fiestas So, NR da Costa F, CF Dos Santos, G Corrêa, MDC Cipitelli, M Dornelas R, LJ de Souza, PV Damasco, RV da Cunha, FB Dos Santos, LM de Oliveir, EL de Azeredo Different Profiles of Cytokines, Chemokines and Coagulation Mediators Associated with Severity in Brazilian Patients Infected with Dengue Virus Viruses, 2021-09-08;13(9):. 2021-09-08 [PMID: 34578370] (Human)
• M Stražar, VP Mourits, VACM Koeken, LCJ de Bree, SJCFM Moorlag, LAB Joosten, R van Crevel, H Vlamakis, MG Netea, RJ Xavier The influence of the gut microbiome on BCG-induced trained immunity Genome Biology, 2021-09-22;22(1):275. 2021-09-22 [PMID: 34551799] (Human)
• J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling Cell Reports, 2021-09-21;36(12):109726. 2021-09-21 [PMID: 34551302] (Human)
• MS Shaban, C Müller, C Mayr-Buro, H Weiser, J Meier-Soel, BV Albert, A Weber, U Linne, T Hain, I Babayev, N Karl, N Hofmann, S Becker, S Herold, ML Schmitz, J Ziebuhr, M Kracht Multi-level inhibition of coronavirus replication by chemical ER stress Nature Communications, 2021-09-20;12(1):5536. 2021-09-20 [PMID: 34545074] (Human)
• S Schlichtne, NH Meyer, IM Yasinska, N Aliu, SM Berger, BF Gibbs, E Fasler-Kan, VV Sumbayev Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis International immunopharmacology, 2021-09-17;100(0):108155. 2021-09-17 [PMID: 34543981] (Human)
• N Cappoli, P Aceto, E Tabolacci, D Mezzogori, L Sollazzi, P Navarra, C Dello Russ Effects of remifentanil on human C20 microglial pro-inflammatory activation European review for medical and pharmacological sciences, 2021-08-01;25(16):5268-5274. 2021-08-01 [PMID: 34486703] (Human)
• A Laustsen, RM van der Sl, A Gris-Olive, SS Hernández, E Cemalovic, HQ Tang, LH Pedersen, N Uldbjerg, MR Jakobsen, RO Bak Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells Elife, 2021-09-02;10(0):. 2021-09-02 [PMID: 34473049] (Human)
• D Reddi, L Durant, D Bernardo, A Noble, NR English, P Hendy, GC Clark, JL Prior, ED Williamson, SC Knight In Vitro Priming of Human T Cells by Dendritic Cells Provides a Screening Tool for Candidate Vaccines for Burkholderia pseudomallei Vaccines, 2021-08-22;9(8):. 2021-08-22 [PMID: 34452057] (Human)
• S Ilari, L Vitiello, P Russo, S Proietti, M Mili?, C Muscoli, V Cardaci, C Tomino, G Bonassi, S Bonassi Daily Vegetables Intake and Response to COPD Rehabilitation. The Role of Oxidative Stress, Inflammation and DNA Damage Nutrients, 2021-08-14;13(8):. 2021-08-14 [PMID: 34444947] (Human)
• A Thérien, A Cie?lak, M Verreault, M Perreault, J Trottier, S Gobeil, MC Vohl, O Barbier Omega-3 Polyunsaturated Fatty Acid: A Pharmaco-Nutraceutical Approach to Improve the Responsiveness to Ursodeoxycholic Acid Nutrients, 2021-07-29;13(8):. 2021-07-29 [PMID: 34444777] (Human)
• E Wirthgen, M Hornschuh, IM Wrobel, C Manteuffel, J Däbritz Mimicking of Blood Flow Results in a Distinct Functional Phenotype in Human Non-Adherent Classical Monocytes Biology, 2021-08-04;10(8):. 2021-08-04 [PMID: 34439980] (Human)
• K Wadowska, P B?asiak, A Rzechonek, I Bil-Lula, M ?liwi?ska- New Insights on Old Biomarkers Involved in Tumor Microenvironment Changes and Their Diagnostic Relevance in Non-Small Cell Lung Carcinoma Biomolecules, 2021-08-13;11(8):. 2021-08-13 [PMID: 34439874] (Human)
• M Lesouhaiti, M Gregoire, A Gacouin, V Coirier, A Frerou, C Piau, V Cattoir, E Dumontet, M Revest, P Tattevin, A Roisne, JP Verhoye, E Flecher, Y Le Tulzo, K Tarte, JM Tadié Neutrophil function and bactericidal activity against Staphylococcus aureus after cardiac surgery with cardiopulmonary bypass Journal of leukocyte biology, 2021-08-23;0(0):. 2021-08-23 [PMID: 34425029] (Human)
• G Dunsmore, EP Rosero, S Shahbaz, DM Santer, J Jovel, P Lacy, S Houston, S Elahi Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection PloS Biology, 2021-08-19;19(8):e3001387. 2021-08-19 [PMID: 34411088] (Human)
• Z Cui, H Dabas, BC Leonard, JV Shiah, JR Grandis, DE Johnson Caspase-8 mutations associated with head and neck cancer differentially retain functional properties related to TRAIL-induced apoptosis and cytokine induction Cell Death & Disease, 2021-08-06;12(8):775. 2021-08-06 [PMID: 34362880] (Human)
• JY Park, JS Hyun, JG Jee, SJ Park, D Khang Structural Deformation of MTX Induced by Nanodrug Conjugation Dictate Intracellular Drug Transport and Drug Efficacy International Journal of Nanomedicine, 2021-07-22;16(0):4943-4957. 2021-07-22 [PMID: 34326636] (Human)
• T Katopodi, S Petanidis, K Domvri, P Zarogoulid, D Anestakis, C Charalampi, D Tsavlis, C Bai, H Huang, L Freitag, W Hohenforst, D Matthaios, K Porpodis Kras-driven intratumoral heterogeneity triggers infiltration of M2 polarized macrophages via the circHIPK3/PTK2 immunosuppressive circuit Scientific Reports, 2021-07-29;11(1):15455. 2021-07-29 [PMID: 34326381] (Human)
• B Falcones, H Sanz-Frail, E Marhuenda, I Mendizábal, I Cabrera-Ag, N Malandain, JJ Uriarte, I Almendros, D Navajas, DJ Weiss, R Farré, J Otero Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells Polymers, 2021-07-18;13(14):. 2021-07-18 [PMID: 34301107] (Human)
• LE Cabrera, PT Pekkarinen, M Alander, KHA Nowlan, NA Nguyen, S Jokiranta, S Kuivanen, A Patjas, S Mero, SH Pakkanen, S Heinonen, A Kantele, O Vapalahti, E Kekäläinen, T Strandin Characterization of low-density granulocytes in COVID-19 PloS Pathogens, 2021-07-06;17(7):e1009721. 2021-07-06 [PMID: 34228753] (Human)
• V Mocanu, Z Zhang, EC Deehan, DH Kao, N Hotte, S Karmali, DW Birch, KK Samarasing, J Walter, KL Madsen Fecal microbial transplantation and fiber supplementation in patients with severe obesity and metabolic syndrome: a randomized double-blind, placebo-controlled phase 2 trial Nature Medicine, 2021-07-05;27(7):1272-1279. 2021-07-05 [PMID: 34226737] (Human)
• JK Park, S Shon, HJ Yoo, DH Suh, D Bae, J Shin, JH Jun, N Ha, H Song, YI Choi, T Pap, YW Song Inhibition of histone deacetylase 6 suppresses inflammatory responses and invasiveness of fibroblast-like-synoviocytes in inflammatory arthritis Arthritis Research & Therapy, 2021-07-05;23(1):177. 2021-07-05 [PMID: 34225810] (Human)
• M Busch, AAM Kämpfer, RPF Schins An inverted in vitro triple culture model of the healthy and inflamed intestine: Adverse effects of polyethylene particles Chemosphere, 2021-06-28;284(0):131345. 2021-06-28 [PMID: 34216924] (Human)
• AL Martel, NL Fraleigh, E Picard, JD Lewicky, G Pawelec, H Lee, GW Ma, L Mousavifar, R Roy, HT Le Novel immunomodulatory properties of low dose cytarabine entrapped in a mannosylated cationic liposome International journal of pharmaceutics, 2021-07-01;0(0):120849. 2021-07-01 [PMID: 34216770] (Human)
• KEC Blokland, H Habibie, T Borghuis, GJ Teitsma, M Schuliga, BN Melgert, DA Knight, CA Brandsma, SD Pouwels, JK Burgess Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM Cells, 2021-06-29;10(7):. 2021-06-29 [PMID: 34209854] (Human)
• J Budzianows, J Hiczkiewic, K ?ojewska, E Kawka, R Rutkowski, K Korybalska Predictors of Early-Recurrence Atrial Fibrillation after Catheter Ablation in Women and Men with Abnormal Body Weight Journal of Clinical Medicine, 2021-06-18;10(12):. 2021-06-18 [PMID: 34207297] (Human)
• E Jover, L Matilla, M Garaikoetx, A Fernández-, P Muntendam, F Jaisser, P Rossignol, N López-Andr Beneficial Effects of Mineralocorticoid Receptor Pathway Blockade against Endothelial Inflammation Induced by SARS-CoV-2 Spike Protein Biomedicines, 2021-06-03;9(6):. 2021-06-03 [PMID: 34204890] (Human)
• V Mocanu, H Park, J Dang, N Hotte, A Thiesen, M Laffin, H Wang, D Birch, K Madsen Timing of Tributyrin Supplementation Differentially Modulates Gastrointestinal Inflammation and Gut Microbial Recolonization Following Murine Ileocecal Resection Nutrients, 2021-06-17;13(6):. 2021-06-17 [PMID: 34204288] (Mouse)
• J Xing, X Zhou, M Fang, E Zhang, LJ Minze, Z Zhang DHX15 is required to control RNA virus-induced intestinal inflammation Cell Reports, 2021-06-22;35(12):109205. 2021-06-22 [PMID: 34161762] (Human)
• Y Li, C Bax, J Patel, T Vazquez, A Ravishanka, MM Bashir, M Grinnell, D Diaz, VP Werth Plasma-derived DNA containing-extracellular vesicles induce STING-mediated proinflammatory responses in dermatomyositis Theranostics, 2021-05-21;11(15):7144-7158. 2021-05-21 [PMID: 34158841] (Human)
• YC Hu, IJ Tsai, HY Hsu, BL Chiang, YH Yang Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production Arthritis Research & Therapy, 2021-06-16;23(1):171. 2021-06-16 [PMID: 34134755] (Human)
• LG Lima, S Ham, H Shin, EPZ Chai, ESH Lek, RJ Lobb, AF Müller, S Mathivanan, B Yeo, Y Choi, BS Parker, A Möller Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Nature Communications, 2021-06-10;12(1):3543. 2021-06-10 [PMID: 34112803] (Human)
• CM Yamazaki, A Yamaguchi, Y Anami, W Xiong, Y Otani, J Lee, NT Ueno, N Zhang, Z An, K Tsuchikama Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance Nature Communications, 2021-06-10;12(1):3528. 2021-06-10 [PMID: 34112795] (Human)
• SL Mathiasen, L Gall-Mas, IS Pateras, SDP Theodorou, MRJ Namini, MB Hansen, OCB Martin, CK Vadivel, K Ntostoglou, D Butter, M Givskov, C Geisler, AN Akbar, VG Gorgoulis, T Frisan, N Ødum, T Krejsgaard Bacterial genotoxins induce T�cell senescence Cell Reports, 2021-06-08;35(10):109220. 2021-06-08 [PMID: 34107253] (Human)
• CY Wu, WL Fan, YM Chiu, HY Yang, WI Lee, JL Huang Lipopolysaccharide stimulation test on cultured PBMCs assists the discrimination of cryopyrin-associated periodic syndrome from systemic juvenile idiopathic arthritis Scientific Reports, 2021-06-07;11(1):11903. 2021-06-07 [PMID: 34099791] (Human)
• M Sueiro-Oli, J Scott, S Gago, D Petrovic, E Kouroussis, J Zivanovic, Y Yu, M Strobel, C Cunha, D Thomson, R Fortune-Gr, S Thusek, P Bowyer, A Beilhack, A Carvalho, E Bignell, MR Filipovic, J Amich Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response PloS Biology, 2021-06-01;19(6):e3001247. 2021-06-01 [PMID: 34061822] (Human)
• MCC Volkweis, GW Neculqueo, RDS Freitas, APA Dagnino, GG Fritscher, TQ Irigaray, MM Campos Psychological symptoms and salivary inflammatory biomarkers in patients with dentofacial deformities: a case-control study Scientific Reports, 2021-05-26;11(1):11083. 2021-05-26 [PMID: 34040126] (Human)
• CM Abreu, MT Cerqueira, RP Pirraco, L Gasperini, RL Reis, AP Marques Rescuing key native traits in cultured dermal papilla cells for human hair regeneration Journal of advanced research, 2020-11-04;30(0):103-112. 2020-11-04 [PMID: 34026290] (Human)
• L Feng, L Liang, S Zhang, J Yang, Y Yue, X Zhang HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway Autophagy, 2021-05-24;0(0):1-20. 2021-05-24 [PMID: 34024230] (Rat)
• PK Fazeli, MA Bredella, OG Pachon-Peñ, W Zhao, X Zhang, AT Faje, M Resulaj, SP Polineni, TM Holmes, H Lee, EK O'Donnell, OA MacDougald, MC Horowitz, CJ Rosen, A Klibanski The dynamics of human bone marrow adipose tissue in response to feeding and fasting JCI Insight, 2021-06-22;0(0):. 2021-06-22 [PMID: 33974568] (Human)
• L Liang, Q Zhou, L Feng Decreased microRNA-155 in Behcet's disease leads to defective control of autophagy thereby stimulating excessive proinflammatory cytokine production Arthritis Research & Therapy, 2021-05-06;23(1):135. 2021-05-06 [PMID: 33957967] (Human)
• N Bozorgmehr, S Mashhouri, E Perez Rose, L Xu, S Shahbaz, W Sligl, M Osman, DJ Kutsogiann, E MacIntyre, CR O'Neil, S Elahi Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection MBio, 2021-05-04;12(3):. 2021-05-04 [PMID: 33947753] (Human)
• T Koudstaal, D van Uden, JAC van Hulst, P Heukels, IM Bergen, LW Geenen, VJM Baggen, AE van den Bo, LM van den To, PP Chandoesin, M Kool, E Boersma, RW Hendriks, KA Boomars Plasma markers in pulmonary hypertension subgroups correlate with patient survival Respiratory Research, 2021-05-04;22(1):137. 2021-05-04 [PMID: 33947407] (Human)
• HL Lee, CE Yeum, H Lee, J Oh, JT Kim, WJ Lee, Y Ha, YI Yang, KN Kim Peripheral Nerve-Derived Stem Cell Spheroids Induce Functional Recovery and Repair after Spinal Cord Injury in Rodents International Journal of Molecular Sciences, 2021-04-16;22(8):. 2021-04-16 [PMID: 33923671] (Human)
• R Song, Y Gao, I Dozmorov, V Malladi, I Saha, MM McDaniel, S Parameswar, C Liang, C Arana, B Zhang, B Wakeland, J Zhou, MT Weirauch, LC Kottyan, EK Wakeland, C Pasare IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility Cell Reports, 2021-03-23;34(12):108891. 2021-03-23 [PMID: 33761354] (Human)
• JH Jeong, SJ Choi, SM Ahn, JS Oh, YG Kim, CK Lee, B Yoo, S Hong Neutrophil extracellular trap clearance by synovial macrophages in gout Arthritis Research & Therapy, 2021-03-19;23(1):88. 2021-03-19 [PMID: 33741037] (Human)
• MS Phuong, RE Hernandez, DJ Wolter, LR Hoffman, S Sad Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response Cell Death & Disease, 2021-03-04;12(3):241. 2021-03-04 [PMID: 33664232] (Human)
• AYY Tam, AL Horwell, SL Trinder, K Khan, S Xu, V Ong, CP Denton, JT Norman, AM Holmes, G Bou-Ghario, DJ Abraham Selective deletion of connective tissue growth factor attenuates experimentally-induced pulmonary fibrosis and pulmonary arterial hypertension The international journal of biochemistry & cell biology, 2021-03-01;134(0):105961. 2021-03-01 [PMID: 33662577] (Human)
• N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, AIM Bantan, JG Cronin, D Avancini, GW Jones, DK Finlay, KH Vousden, EE Vincent, CA Thornton Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation Nature Communications, 2021-02-22;12(1):1209. 2021-02-22 [PMID: 33619282] (Human)
• C Vaamonde-G, N Flórez-Fer, MD Torres, MJ Lamas-Vázq, FJ Blanco, H Domínguez, R Meijide-Fa Study of fucoidans as natural biomolecules for therapeutical applications in osteoarthritis Carbohydrate polymers, 2021-01-26;258(0):117692. 2021-01-26 [PMID: 33593565] (Human)
• JI Alexander, DB Vendramini, R Francescon, T Luong, J Franco-Bar, N Shah, JC Gardiner, E Nicolas, KS Raghavan, E Cukierman Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinoma Scientific Reports, 2021-02-15;11(1):3802. 2021-02-15 [PMID: 33589694] (Human)
• P Kvacskay, N Yao, JH Schnotz, R Scarpone, RA Carvalho, KD Klika, W Merkt, T Tretter, HM Lorenz, LO Tykocinski Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy? Arthritis Research & Therapy, 2021-02-15;23(1):56. 2021-02-15 [PMID: 33588937] (Human)
• Y Hosokawa, I Hosokawa, K Ozaki, T Matsuo The Polymethoxy Flavonoid Sudachitin Inhibits Interleukin-1&beta-Induced Inflammatory Mediator Production in Human Periodontal Ligament Cells BioMed Research International, 2021-01-28;2021(0):8826586. 2021-01-28 [PMID: 33575345] (Human)
• AD Brunaugh, H Seo, Z Warnken, L Ding, SH Seo, HDC Smyth Development and evaluation of inhalable composite niclosamide-lysozyme particles: A broad-spectrum, patient-adaptable treatment for coronavirus infections and sequalae PLoS ONE, 2021-02-11;16(2):e0246803. 2021-02-11 [PMID: 33571320] (Human)
• M Dabaghi, N Saraei, G Xu, A Chandiramo, J Yeung, JP Nguyen, M Vukmirovic, PR Selvaganap, JA Hirota PHAIR: a biosensor for pH measurement in air-liquid interface cell culture Scientific Reports, 2021-02-10;11(1):3477. 2021-02-10 [PMID: 33568708] (Human)
• X Chu, Y Gu, W Sheng, J Sun, JA Morgan, DF Lewis, DB Cooper, CE McCathran, Y Wang Downregulation of miR-126-3p expression contributes to increased inflammatory response in placental trophoblasts in preeclampsia Journal of reproductive immunology, 2021-02-01;144(0):103281. 2021-02-01 [PMID: 33549904] (Human)
• P Jitprasert, M Khamphio, P Petsrichua, VGH Eijsink, W Poolsri, C Muanprasat, K Rangnoi, M Yamabhai Anti-inflammatory activity of soluble chito-oligosaccharides (CHOS) on VitD3-induced human THP-1 monocytes PLoS ONE, 2021-02-03;16(2):e0246381. 2021-02-03 [PMID: 33534833] (Human)
• MS Coates, EWFW Alton, GW Rapeport, JC Davies, K Ito Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway PLoS ONE, 2021-02-01;16(2):e0246050. 2021-02-01 [PMID: 33524056] (Human)
• RP Madeira, LM Dal'Mas Ro, P de Cássia, C Mady, BM Ianni, AC Torrecilha New Biomarker in Chagas Disease: Extracellular Vesicles Isolated from Peripheral Blood in Chronic Chagas Disease Patients Modulate the Human Immune Response Journal of Immunology Research, 2021-01-11;2021(0):6650670. 2021-01-11 [PMID: 33506056] (Human)
• Z Iqbal, A Kalteniece, M Ferdousi, S Adam, L D'Onofrio, JH Ho, AP Rao, S Dhage, S Azmi, Y Liu, R Donn, RA Malik, H Soran Corneal Keratocyte Density and Corneal Nerves Are Reduced in Patients With Severe Obesity and Improve After Bariatric Surgery Investigative Ophthalmology & Visual Science, 2021-01-04;62(1):20. 2021-01-04 [PMID: 33475689] (Human)
• SM Anil, N Shalev, AC Vinayaka, S Nadarajan, D Namdar, E Belausov, I Shoval, KA Mani, G Mechrez, H Koltai Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages Scientific Reports, 2021-01-14;11(1):1462. 2021-01-14 [PMID: 33446817] (Human)
• R Björkenhei, E Jämsen, E Eriksson, P Uppstu, L Aalto-Setä, L Hupa, KK Eklund, M Ainola, NC Lindfors, J Pajarinen Sintered S53P4 bioactive glass scaffolds have anti-inflammatory properties and stimulate osteogenesis in vitro European cells & materials, 2021-01-03;41(0):15-30. 2021-01-03 [PMID: 33389745] (Human)
• LJ Williams, SG Tristram, GR Zosky Iron Oxide Particles Alter Bacterial Uptake and the LPS-Induced Inflammatory Response in Macrophages International Journal of Environmental Research and Public Health, 2020-12-28;18(1):. 2020-12-28 [PMID: 33379200] (Human)
• P Peterlin, J Gaschet, T Guillaume, A Garnier, M Eveillard, A Le Bourgeo, M Cherel, C Debord, Y Le Bris, O Theisen, C Godon, B Mahé, V Dubruille, S Wuilleme, C Touzeau, T Gastinne, N Blin, A Lok, B Tessoulin, S Le Gouill, P Moreau, MC Béné, P Chevallier A new cytokine-based dynamic stratification during induction is highly predictive of survivals in acute myeloid leukemia Cancer Medicine, 2020-12-25;0(0):. 2020-12-25 [PMID: 33369136] (Human)
• H Salvator, A Buenestado, M Brollo, E Naline, T Victoni, E Longchamp, H Tenor, S Grassin-De, P Devillier Clinical Relevance of the Anti-inflammatory Effects of Roflumilast on Human Bronchus: Potentiation by a Long-Acting Beta-2-Agonist Frontiers in Pharmacology, 2020-12-08;11(0):598702. 2020-12-08 [PMID: 33363471] (Human)
• M Estermann, YL Huang, D Septiadi, D Ritz, CY Liang, F Jacob, B Drasler, A Petri-Fink, V Heinzelman, B Rothen-Rut Patient-derived and artificial ascites have minor effects on MeT-5A mesothelial cells and do not facilitate ovarian cancer cell adhesion PLoS ONE, 2020-12-03;15(12):e0241500. 2020-12-03 [PMID: 33270665] (Human)
• WM Abdelwahab, A Riffey, C Buhl, C Johnson, K Ryter, JT Evans, DJ Burkhart Co-Adsorption of Synthetic Mincle Agonists and Antigen to Silica Nanoparticles for Enhanced Vaccine Activity: A Formulation Approach to Co-Delivery Int J Pharm, 2020-11-27;0(0):120119. 2020-11-27 [PMID: 33249249] (Human)
• M De, A Bhushan, S Chinnaswam Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-&lambda3 or IFN-&lambda4 show distinct phenotypes J Leukoc Biol, 2020-11-17;0(0):. 2020-11-17 [PMID: 33205487] (Human)
• CA Ciocan-Car, A Jurj, O Zanoaga, R Cojocneanu, LA Pop, A Moldovan, C Moldovan, AA Zimta, L Raduly, C Pop-Bica, M Buse, L Budisan, P Virag, A Irimie, SMG Diaz, I Berindan-N, C Braicu New insights in gene expression alteration as effect of doxorubicin drug resistance in triple negative breast cancer cells J Exp Clin Cancer Res, 2020-11-13;39(1):241. 2020-11-13 [PMID: 33187552] (Human)
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FAQs for IL-6 (DY206). (Showing 1 - 2 of 2 FAQs).

1. I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?
   • We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.
2. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: IL6