Human IL-38/IL-1F10 DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human IL-38/IL-1F10 DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-38/IL-1F10 DuoSet ELISA, 5 Plate

• FIL1- theta
• FKSG75
• IL1F10
• IL-1HY2
• IL38
• IL-38
• interleukin 1 family, member 10 (theta)
• UNQ6119/PRO20041

Background

Human IL-38/IL-1F10 is a secreted cytokine belonging to the IL-1 family. It is synthesized as a 152 amino acid mature protein that lacks an identifiable signal sequence. It binds to soluble IL-1 R1. Human IL-38 shares 82% aa sequence identity with mouse IL-1F10. Human IL-38 also shares 39% and 27% aa sequence identity with IL-1ra and IL-1 beta, respectively.

Publications for IL-38/IL-1F10 (DY9110-05)(10)

Publications using DY9110-05

• Shepelkova, GS;Evstifeev, VV;Berezovskiy, YS;Ergeshova, AE;Tarasov, RV;Bagirov, MA;Yeremeev, VV; Characteristics of Pulmonary Inflammation in Patients with Different Forms of Active Tuberculosis International journal of molecular sciences 2024-11-02 [PMID: 39519346] (Human)
• LU Teufel, CI van der Ma, V Klück, A Simons, A Hoischen, V Vernimmen, LAB Joosten, RJW Arts Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study Cytokine, 2022-12-05;162(0):156102. 2022-12-05 [PMID: 36476991] (Human)
• I Kolotilin Plant-produced recombinant cytokines IL-37b and IL-38 modulate inflammatory response from stimulated human PBMCs Scientific Reports, 2022-11-14;12(1):19450. 2022-11-14 [PMID: 36376518] (Human)
• X Sun, J Zhou, W Huang, B Wang, Y Zhang, L Duan, W Chen Association between IL-38 and inflammatory indicators in patients with bacterial pneumonia Cytokine, 2022-11-12;161(0):156052. 2022-11-12 [PMID: 36375397] (Human)
• E The, DM de Graaf, Y Zhai, Q Yao, L Ao, DA Fullerton, CA Dinarello, X Meng Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3 Proceedings of the National Academy of Sciences of the United States of America, 2022-08-29;119(36):e2202577119. 2022-08-29 [PMID: 36037361] (Human)
• J Cao, L Hua, S Zhang, J Tang, F Ke, Z Wu, G Xue Serum interleukin-38 levels correlated with insulin resistance, liver injury and lipids in non-alcoholic fatty liver disease Lipids in Health and Disease, 2022-08-10;21(1):70. 2022-08-10 [PMID: 35948957] (Human)
• DM de Graaf, M Jaeger, ICL van den Mu, RT Horst, K Schraa, J Zwaag, M Kox, M Fujita, T Yamauchi, L Mercurio, S Madonna, JHW Rutten, J de Graaf, NP Riksen, FL van de Vee, MG Netea, LAB Joosten, CA Dinarello Reduced concentrations of the B cell cytokine Interleukin 38 are associated with cardiovascular disease risk in overweight subjects Eur J Immunol, 2020-11-19;0(0):. 2020-11-19 [PMID: 33125159] (Human)
• I Tsilioni, H Pantazopou, P Conti, SE Leeman, TC Theoharide IL-38 inhibits microglial inflammatory mediators and is decreased in amygdala of children with autism spectrum disorder Proc. Natl. Acad. Sci. U.S.A., 2020-06-29;0(0):. 2020-06-29 [PMID: 32601180] (Human)
• D Talabot-Ay, L Mermoud, J Borowczyk, J Drukala, M Wolnicki, A Modarressi, WH Boehncke, N Brembilla, G Palmer Interleukin-38 interacts with destrin/actin-depolymerizing factor in human keratinocytes PLoS ONE, 2019-11-26;14(11):e0225782. 2019-11-26 [PMID: 31770407] (Human)
• X Qin, M Liu, S Zhang, C Wang, T Zhang The role of IL-36? and its regulation in eosinophilic inflammation in allergic rhinitis Cytokine, 2019-03-01;117(0):84-90. 2019-03-01 [PMID: 30831444] (Human)