Human IL-17E DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human IL-17E DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-17E DuoSet ELISA, 5 Plate

• IL17E
• IL-17E
• IL25
• IL-25
• interleukin 25
• Interleukin-17E
• interleukin-25

Background

The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

Publications for IL-17E/IL-25 (DY1258-05)(8)

Publications using DY1258-05

• Park, JH;Moon, JW;Yang, HW;Song, DJ;Park, IH; Effect of air pollutants on allergic inflammation in structural cells of nasal mucosa Clinical and experimental otorhinolaryngology 2024-03-14 [PMID: 38480529] (Human)
• Yao, X;Chen, Q;Wang, X;Liu, X;Zhang, L; IL-25 induces airway remodeling in asthma by orchestrating the phenotypic changes of epithelial cell and fibrocyte Respiratory research 2023-08-27 [PMID: 37635231] (Human)
• Weng, CM;Lee, MJ;Chao, W;Lin, YR;Chou, CJ;Chen, MC;Chou, CL;Lin Tsai, I;Lin, CH;Fan Chung, K;Kuo, HP; Airway epithelium IgE-Fc?RI Cross-Link Induces Epithelial Barrier Disruption in Severe T2-high Asthma Mucosal immunology 2023-08-01 [PMID: 37536562] (Human)
• ML Tsai, MK Tsai, YG Tsai, YC Lin, YL Hsu, YT Chen, YC Lin, CH Hung Montelukast Increased IL-25, IL-33, and TSLP via Epigenetic Regulation in Airway Epithelial Cells International Journal of Molecular Sciences, 2023-01-08;24(2):. 2023-01-08 [PMID: 36674744] (Human)
• SH Shin, MK Ye, DW Lee, MH Chae, BD Han Nasal Epithelial Cells Activated with Alternaria and House Dust Mite Induce Not Only Th2 but Also Th1 Immune Responses Int J Mol Sci, 2020-04-13;21(8):. 2020-04-13 [PMID: 32294933] (Human)
• Y Xu, J Ye, M Wang, J Liu, Z Wang, H Jiang, D Ye, J Zhang, J Wan The expression of interleukin-25 increases in human coronary artery disease and is associated with the severity of coronary stenosis Anatol J Cardiol, 2020-02-01;23(3):151-159. 2020-02-01 [PMID: 32120360] (Human)
• S Majewski, K Szewczyk, AJ Bia?as, J Mi?kowska-, P Górski, WJ Piotrowski Epithelial Alarmins in Serum and Exhaled Breath in Patients with Idiopathic Pulmonary Fibrosis: A Prospective One-Year Follow-Up Cohort Study J Clin Med, 2019-10-02;8(10):. 2019-10-02 [PMID: 31581688] (Human)
• Chitin-Induced Airway Epithelial Cell Innate Immune Responses Are Inhibited by Carvacrol/Thymol PLoS ONE, 2016-07-27;11(7):e0159459. 2016-07-27 [PMID: 27463381] (Human)

FAQs for IL-17E/IL-25 (DY1258-05). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.