Human CXCL14/BRAK DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human CXCL14/BRAK DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CXCL14

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CXCL14/BRAK DuoSet ELISA, 15 Plate

• BMAC
• Bolekine
• BRAK
• BRAKKEC
• chemokine (C-X-C motif) ligand 14
• Chemokine BRAK
• CXCL14
• CXC-X3
• member 14 (BRAK)
• MIP-2 gamma
• MIP2G
• MIP-2G
• NJACKec
• SCYB14MGC10687
• Small-inducible cytokine B14

Background

Breast and kidney-expressed chemokine (CXCL14/BRAK), also named MIP-2 gamma, kidney-expressed chemokine (KEC), and B cell and monocyte-activating chemokine (BMAC), is a member of CXC chemokine subfamily. Mature human and mouse BRAK differ by only two residues. BRAK transcripts are constitutively expressed at high levels in the basal layer of epidermal keratinocytes and dermal fibroblasts of skin tissues as well as lamina propria cells in normal intestinal tissues.

Publications for CXCL14/BRAK (DY866)(4)

Publications using DY866

• TM Chang, YC Chiang, CW Lee, CM Lin, ML Fang, MC Chi, JF Liu, YR Kou CXCL14 promotes metastasis of non-small cell lung cancer through ACKR2-depended signaling pathway International journal of biological sciences, 2023-02-27;19(5):1455-1470. 2023-02-27 [PMID: 37056937] (Human)
• A Witte, M Chatterjee, F Lang, M Gawaz Platelets as a Novel Source of Pro-Inflammatory Chemokine CXCL14 Cell. Physiol. Biochem., 2017-03-29;41(4):1684-1696. 2017-03-29 [PMID: 28359053] (Human)
• Dai C, Basilico P, Cremona T, Collins P, Moser B, Benarafa C, Wolf M CXCL14 displays antimicrobial activity against respiratory tract bacteria and contributes to clearance of Streptococcus pneumoniae pulmonary infection. J Immunol, 2015-05-11;194(12):5980-9. 2015-05-11 [PMID: 25964486] (Mouse)
• McKinnon CM, Lygoe KA, Skelton L, Mitter R, Mellor H The atypical Rho GTPase RhoBTB2 is required for expression of the chemokine CXCL14 in normal and cancerous epithelial cells. Oncogene, 2008-09-01;27(54):6856-65. 2008-09-01 [PMID: 18762809] (Human)

FAQs for CXCL14/BRAK (DY866). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: CXCL14