Human C1qR1/CD93 Quantikine ELISA Kit

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP

Human C1qR1/CD93 Quantikine ELISA Kit Summary

• Background: The Quantikine Human C1q R1 Immunoassay is a 3.5 hour solid-phase ELISA designed to measure human C1q R1 in cell culture supernates, serum, plasma, saliva, and urine. It contains NS0-expressed recombinant human C1q R1 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human C1q R1 showed linear curves that were parallel to the standard curves o...btained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human C1q R1.
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• Specificity: Natural and recombinant human C1q R1
• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CD93

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human C1qR1/CD93 Quantikine ELISA Kit

• AA4 Antigen
• C1q R1
• C1q receptor 1
• C1q Rp
• C1q/MBL/SPA receptor
• C1qR(P)
• C1qR1
• C1qRp
• CD93 antigenC1qR
• CD93 molecule
• CD93
• CDw93C1QR1
• Collectin Receptor
• Complement component 1 q subcomponent receptor 1
• complement component 1, q subcomponent, receptor 1
• complement component C1q receptor
• dJ737E23.1
• ECSM3
• Ly68
• Matrix-remodeling-associated protein 4
• matrix-remodelling associated 4
• MXRA4

Background

C1q R1 is also known as C1q Rp, collectin receptor, and AA4 antigen. C1q R1 mediates enhanced phagocytosis by monocytes and macrophages upon interaction with soluble defense collagens including C1q, MBL, and SP-A. It is a type I transmembrane glycoprotein expressed on endothelial cells, hematopoietic progenitor cells, platelets, and cells of myeloid origin. C1q R1 has also been identified as a hematopoietic stem cell marker.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for C1qR1/CD93 (DCD930)(4)

Publications using DCD930

• Huerta-Yepez, S;Gonzalez, JD;Sheik, N;Beraki, S;Kathirvel, E;Rodriguez-Frandsen, A;Chen, PC;Sargsyan, T;Mahammad, S;Dybul, MR;Chen, L;Binette, F;Jewett, A; Therapeutic Efficacy of CD34-Derived Allogeneic Dendritic Cells Engineered to Express CD93, CD40L, and CXCL13 in Humanized Mouse Models of Pancreatic Cancer Vaccines 2025-07-12 [PMID: 40733726] (Human)
• M Kielar, P Dumnicka, E Ignacak, A B?dkowska-, A Gala-B??dz, B Maziarz, P Ceranowicz, B Ku?nierz-C Soluble Complement Component 1q Receptor 1 (sCD93) Is Associated with Graft Function in Kidney Transplant Recipients Biomolecules, 2021-11-02;11(11):. 2021-11-02 [PMID: 34827620] (Human)
• U Alehagen, L Shamoun, D Wågsäter Genetic variance and plasma concentration of CD93 is associated with cardiovascular mortality: Results from a 6.7?year follow?up of a healthy community?living elderly population Mol Med Rep, 2020-10-01;22(6):4629-4636. 2020-10-01 [PMID: 33173973] (Human)
• J Ishizaki, A Takemori, K Suemori, T Matsumoto, Y Akita, KE Sada, Y Yuzawa, K Amano, Y Takasaki, M Harigai, Y Arimura, H Makino, M Yasukawa, N Takemori, H Hasegawa Targeted proteomics reveals promising biomarkers of disease activity and organ involvement in antineutrophil cytoplasmic antibody-associated vasculitis Arthritis Res. Ther., 2017-09-29;19(1):218. 2017-09-29 [PMID: 28962592] (Human)

FAQs for C1qR1/CD93 (DCD930). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: CD93