The Quantikine Human C1q R1 Immunoassay is a 3.5 hour solid-phase ELISA designed to measure human C1q R1 in cell culture supernates, serum, plasma, saliva, and urine. It contains NS0-expressed recombinant human C1q R1 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human C1q R1 showed linear curves that were parallel to the standard curves o...btained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human C1q R1.
C1q R1 is also known as C1q Rp, collectin receptor, and AA4 antigen. C1q R1 mediates enhanced phagocytosis by monocytes and macrophages upon interaction with soluble defense collagens including C1q, MBL, and SP-A. It is a type I transmembrane glycoprotein expressed on endothelial cells, hematopoietic progenitor cells, platelets, and cells of myeloid origin. C1q R1 has also been identified as a hematopoietic stem cell marker.
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Publications for C1qR1/CD93 (DCD930)(3)
We have publications tested in 1 confirmed species: Human.