HuC Antibody [DyLight 550]

Product Discontinued

HuC Antibody [DyLight 550] Summary

• Immunogen: ELAV(embryonic lethal, abnormal vision, Drosophila)-like 3(Hu antigen C). (Uniprot# Q14576)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ELAVL3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for HuC Antibody [DyLight 550]

• DKFZp547J036
• ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
• ELAV-like protein 3
• Hu antigen C
• Hu-antigen C
• HuC
• HUCL
• HUCParaneoplastic cerebellar degeneration-associated antigen
• MGC20653
• PLE21Paraneoplastic limbic encephalitis antigen 21

Background

HuC is a member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ELAVL3