Human HTRA1/PRSS11 ELISA Kit (Colorimetric)

ELISA: Human HTRA1/PRSS11 ELISA Kit (Colorimetric) [NBP2-76585] - Samples were spiked with high concentrations of Human HTRA1/PRSS11 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Human HTRA1/PRSS11 ELISA Kit (Colorimetric) [NBP2-76585] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 0.313 - 20ng/mL
• Sensitivity: 0.188ng/mL

Human HTRA1/PRSS11 ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Human HTRA1 in samples. No significant cross-reactivity or interference between Human HTRA1 and analogues was observed.
• Standard Curve Range: 0.313 - 20ng/mL
• Sensitivity: 0.188ng/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: CV% < 4.64
• Intra-Assay: CV% < 4.5
• Spike Recovery: 85-106%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: HTRA1

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human HTRA1/PRSS11 ELISA Kit (Colorimetric)

• ARMD7
• EC 3.4.21
• EC 3.4.21.108
• High-temperature requirement A serine peptidase 1
• HtrA serine peptidase 1
• HTRA1
• IGFBP5-protease
• L56
• ORF480
• PRSS11
• Serine protease 11
• serine, 11 (IGF binding)

Background

htrA1 encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for HTRA1/PRSS11 ELISA Kit (NBP2-76585)(1)

Publication using NBP2-76585

• Chang YJ, Jenny LA, Li YS et al. CRISPR editing demonstrates rs10490924 raised oxidative stress in iPSC-derived retinal cells from patients with ARMS2/HTRA1-related AMD Proceedings of the National Academy of Sciences of the United States of America 2023-05-09 [PMID: 37126685] (ELISA)

FAQs for HTRA1/PRSS11 ELISA Kit (NBP2-76585). (Showing 1 - 1 of 1 FAQ).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: HTRA1