Hu, Mu, Rt, Bv, Ca, PmApplications:
WB, Simple Western, ICC/IFHost:
Hu, Mu, RtApplications:
ICC/IF, IHC, IHC-PHost:
htrA1 encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
|Product By Gene ID
- EC 184.108.40.206
- EC 3.4.21
- Serine protease 11
- High-temperature requirement A serine peptidase 1
- serine, 11 (IGF binding)
- HtrA serine peptidase 1
Bioinformatics Tool for HTRA1/PRSS11
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