HSF4 Antibody (504524) [CoraFluor™ 1]

• Reactivity: Hu, Mu
• Applications: WB
• Clone: 504524
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

HSF4 Antibody (504524) [CoraFluor™ 1] Summary

• Immunogen: E. coli-derived recombinant human HSF4
  Ser309-Pro463
  Accession # BAA13433
• Specificity: Detects endogenous human and mouse HSF4 in Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: HSF4
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for HSF4 Antibody (504524) [CoraFluor™ 1]

• ATHSF4
• AT-HSFB1
• cataract, Marner
• CTM
• heat shock factor protein 4
• heat shock transcription factor 4CTM
• hHSF4
• HSF 4
• HSF4
• HSFB1
• HSTF 4

Background

HSF4 is a gene which codes for a DNA-binding protein that binds to heat shock promoter elements and is expressed in the heart, skeletal muscle, eyes and brain, with an isoform with a length of 492 amino acids and a weight of approximately 53 kDa which activates transcription, and a shorter isoform with a length of 462 amino acids and a weight of approximately 50 kDa that represses transcription. Current studies are being done on several disorders and diseases relating to this gene including cataract, otitis media, cervical adenitis, Scheuermann's disease, Ritter's disease, and impetigo. HSF4 has also been shown to have interactions with CDK2AP2, NUDT21, C5orf54, MAPK1, and DUSP26.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HSF4