HSD17B6 Antibody

Images

 
Western Blot: HSD17B6 Antibody [NBP1-31672] - Sample (30 ug of whole cell lysate) A: Molt-4 10% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP1-31672] - Paraffin-embedded colon ca, using antibody at 1:500 dilution.

Product Details

Summary
Reactivity Hu, RMSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.71 mg/ml

Order Details

HSD17B6 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human HSD17B6. The exact sequence is proprietary.
Localization
Microsome membrane, Peripheral membrane protein, Lumenal side, Early endosome membrane, Peripheral membrane protein, Lumenal side
Predicted Species
Rhesus Macaque (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HSD17B6
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.71 mg/ml
Purity
Immunogen affinity purified

Alternate Names for HSD17B6 Antibody

  • 17-beta-HSD 6
  • 17-beta-HSD6
  • 17-beta-hydroxysteroid dehydrogenase type 6
  • 3(alpha->beta)-hydroxysteroid epimerase
  • 3-alpha->beta-HSE
  • EC 1.1.1
  • EC 1.1.1.105
  • EC 1.1.1.62
  • EC 1.1.1.63
  • HSE3-hydroxysteroid epimerase
  • hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
  • hydroxysteroid (17-beta) dehydrogenase 6
  • NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase
  • Oxidative 3-alpha hydroxysteroid dehydrogenase
  • oxidative 3-alpha-hydroxysteroid-dehydrogenase
  • oxidoreductase
  • retinol dehydrogenase
  • RODH3(alpha->beta)-hydroxysteroid epimerasel
  • SDR9C6
  • short chain dehydrogenase/reductase family 9C, member 6,3-alpha->beta-hydroxysteroid epimerase

Background

The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HSD17B6