HSD17B6 Antibody - BSA Free

Western Blot: HSD17B6 Antibody [NBP1-31672] - Sample (30 ug of whole cell lysate) A: Molt-4 10% SDS PAGE; antibody diluted at 1:1000.

Immunohistochemistry-Paraffin: HSD17B6 Antibody [NBP1-31672] - Paraffin-embedded colon ca, using antibody at 1:500 dilution.

• Reactivity: Hu, RM
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

HSD17B6 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit HSD17B6 Antibody - BSA Free (NBP1-31672) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human HSD17B6. The exact sequence is proprietary.
• Localization: Microsome membrane, Peripheral membrane protein, Lumenal side, Early endosome membrane, Peripheral membrane protein, Lumenal side
• Predicted Species: Rhesus Macaque (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HSD17B6
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 36 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for HSD17B6 Antibody - BSA Free

• 17-beta-HSD 6
• 17-beta-HSD6
• 17-beta-hydroxysteroid dehydrogenase type 6
• 3(alpha->beta)-hydroxysteroid epimerase
• 3-alpha->beta-HSE
• EC 1.1.1
• EC 1.1.1.105
• EC 1.1.1.62
• EC 1.1.1.63
• HSE3-hydroxysteroid epimerase
• hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
• hydroxysteroid (17-beta) dehydrogenase 6
• NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase
• Oxidative 3-alpha hydroxysteroid dehydrogenase
• oxidative 3-alpha-hydroxysteroid-dehydrogenase
• oxidoreductase
• retinol dehydrogenase
• RODH3(alpha->beta)-hydroxysteroid epimerasel
• SDR9C6
• short chain dehydrogenase/reductase family 9C, member 6,3-alpha->beta-hydroxysteroid epimerase

Background

The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: HSD17B6